45 - Inflammation, hormones and the hidden cause of chronic disease
The Dr Louise Newson Podcast
Dr Louise Newson
4.7 • 933 Ratings
🗓️ 3 February 2026
⏱️ 28 minutes
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Summary
In this episode, Dr Louise Newson is joined by Professor Robert Lufkin, physician, medical school professor and author, to explore how inflammation and metabolic dysfunction lie at the heart of many of today’s chronic diseases.
They discuss why conditions such as heart disease, diabetes, cancer, dementia and mental illness are often treated as separate problems, when in reality they share the same inflammatory and metabolic origins.
The conversation also looks at the central role of hormones in regulating inflammation, mitochondrial function and long-term health, and why progesterone, estradiol and testosterone may be among the most powerful disease-modifying treatments we already have.
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Transcript
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| 0:00.0 | This is a great conversation with Dr Robert Lufkin, who is a US doctor, |
| 0:05.6 | and he's written a book about lies he learned at medical school. |
| 0:10.0 | He talks about things he learned at medical school aren't quite what he knows now. |
| 0:16.0 | And we know this because evidence is changing all the time. |
| 0:19.4 | But he talks a lot about chronic diseases |
| 0:21.6 | and the underlying cause being related to inflammation, something I'm very fond of. So thinking |
| 0:28.2 | about how we as individuals can reduce inflammation through our lifestyle and hormones, of course, |
| 0:34.0 | really important. So it's a very riveting conversation for you to enjoy and to learn from. |
| 0:41.9 | So Rob, I've been stalking you for a little while and I read your book quite soon after it came out. |
| 0:49.0 | And to be honest, so many pages I've turned down and I've gone back and read and reread it. And it resonated so much |
| 0:57.3 | with the way that my mind, my brain has changed over the last 30 years of being a doctor. |
| 1:04.3 | And when I came out of medical school, I thought I knew everything and I thought everything I |
| 1:09.1 | learned at medical school would just put me in good stead |
| 1:11.6 | until the time I retired. And it's changed every day I learn new things from my patients and every day |
| 1:18.9 | I learn new things from reading different articles and scientific evidence and literature |
| 1:22.9 | and reading books like this as well. So your book is called Lies. |
| 1:27.6 | I taught in medical school how conventional medicine is making you sicker |
| 1:32.2 | and what you can do to save your life. |
| 1:35.2 | So it's a pretty powerful cover here. |
| 1:37.5 | So can you just explain a bit about your background |
| 1:40.9 | and then why you wrote this book, |
| 1:43.5 | which is a New York Times bestseller, I like to add. |
... |
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