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Diet Doctor Podcast

#44 - Angela Poff, PhD

Diet Doctor Podcast

dietdoctorpodcast

Science

4.8711 Ratings

🗓️ 21 April 2020

⏱️ 53 minutes

🧾️ Download transcript

Summary

Cancer. The word no one wants to hear. A terrifying diagnosis with treatments aptly named "toxic" therapies. Dr. Angela Poff is a leading researcher investigating revolutionary, non-toxic metabolic therapies for cancer. Ketones are a leading candidate for that role. How do different types of cancer respond to ketones? How do different types of ketones affect cancer cells? The answers to these questions could revolutionize the way we treat one of the most feared and deadly diseases. Both ketogenic diets and exogenous ketone therapy show tremendous promise, but the science is still mostly in the pre-clinical stage, meaning non-human studies. Dr. Poff is on the front lines of this important research, helping us make progress toward evidence-based answers.

Transcript

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0:00.0

Welcome back to the Diet Doctor Podcast.

0:05.1

I'm your host, Dr. Brett Schur.

0:07.3

Today I'm joined by Dr. Angela Poff.

0:09.3

Now, Angela's a research associate in the Department of Molecular Pharmacology and Physiology

0:14.1

in the University of South Florida.

0:17.0

And she's working in the same lab as Dr. Dominic DiAgostino, but she's really flourished in her own right

0:22.8

and has sort of taken over the cancer side of that lab

0:26.3

looking at nutritional interventions for cancer.

0:29.8

And it's a really exciting field

0:31.6

because when you think about it, how prevalent cancer is,

0:33.8

pretty much everybody has been touched by cancer,

0:36.4

either personally or by a loved one.

0:38.7

In cancer therapies, although you can say we've progressed, we probably haven't progressed

0:42.9

as quickly as many people would have hoped with this sort of genetic basis of cancer.

0:47.6

Well, now there's this resurgence of this whole other concept of the metabolic basis of

0:52.3

cancer. And how can we treat metabolic disease with diet, with nutrition, and specifically with

0:57.7

a ketogenic diet and maybe even exogenous ketones.

1:01.2

Now, there's a lot of excitement about this field, but as you'll hear Dr. Poff and I discuss,

1:05.9

it's still a lot of pre-clinical evidence, which puts us in a bit of a tough balancing act of how strongly to

1:12.4

promote this because people want a cure, people want something to help, they'll latch on to

1:17.0

anything. And if we have something that can help them, we should be promoting it. But does the

1:21.7

strength of the evidence support the strength of the recommendation? So we do have to be a little

...

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