4.8 • 626 Ratings
🗓️ 28 September 2021
⏱️ 90 minutes
🧾️ Download transcript
In this episode we discuss the potential impact of dietary polyphenols on cognitive health; including cogitnitve funciton, memory, and risk of dementia and Alzeimher's. We talk about some potential mechanisms, cohort studies, and then direct controlled trials.
You can find the show notes at sigmanutrition.com/episode406/ and/or support the podcast at patreon.com/sigmanutrition
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0:00.0 | Hello and welcome to another episode of Sigma Nutrition Radio. |
0:17.0 | This is episode 406 of the podcast. My name is Danny Lennon and of course here with me is Alan Flanagan. |
0:26.1 | Alan, how are you, sir? I am bathed in a sea of fat. |
0:33.6 | Their god is sort of just drenched in fat. As I've been telling Alan, I've been playing around with a soundboard here and I've been having way too much fun. |
0:42.4 | We're a quote shot. |
0:45.0 | So apologies for anyone if I'm going to wreck their head with these random things. |
0:50.3 | But in terms of my greeting to you, I also will say, I wish you a sea of fat. I hope that you are say I wish you a sea of fat I hope that you |
0:55.6 | are engulfed in a sea of fat thank you we're a coach yeah yeah how are things how is life |
1:03.0 | things things are things are good I think I was telling I think we talked about it briefly before |
1:08.6 | but based on our energy expenditure data from a lab study we did in 2019, our postdoc, Dr. Leonie Ruddick Collins, who's just fantastic, built a model to try and account for circadian variation in resting metabolic rate, right? |
1:29.6 | Because that would go into the calculation of thermic-effective feeding at a particular point in the day if you're measuring TEP. |
1:37.3 | So we've just had a paper accepted in J-KEM, Journal of Clinical Endocrinology and Metabolism, which was great. |
1:48.0 | It was great to get that in. |
1:49.0 | This is the kind of part of the Big Breakfast study, so the joint grant between the University of Aberdeen and ourselves at Surrey. |
1:56.0 | So yeah, it's a really interesting kind of way of trying to think about this because you |
2:04.2 | often will get studies that show this quite pronounced difference, suppose a difference between |
2:10.1 | the thermic effect of feeding in response to breakfast versus dinner. |
2:13.2 | And actually that method of calculating that shows that may actually be more of a kind of what |
2:19.4 | you're seeing as an artifact really of a kind of mathematical error in actually calculating |
2:24.7 | tests. |
2:25.7 | So that, yeah, it's still in that accepted manuscript form, which I actually can't stand looking |
2:32.9 | at papers when accepted manuscript is like plastered |
... |
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