Hello and welcome to another episode of Sigma Nutrition Radio. This is episode 381 of the podcast. My name is Danny Lennon,

and in a few moments I'll be joined by today's co-host Alan Flanagan. And we are going to be

talking with Professor Chris Packard, who holds an honorary professorship of vascular biochemistry

at the University of Glasgow, and who is acknowledged as truly

one of the leading researchers in the world in the field of atherosclerosis research, lipoprotein

metabolism, and so on. And over the course of many years, his work has focused really on

those primary two areas of

atherosclerosis research, the lipoprotein metabolism and how it is affected by diet and drugs,

and then also on several large-scale clinical trials of lipid lowering agents.

And his group have looked at things all the way from, like I say,

the metabolism, all the up to use of various different drugs, to looking at inflammation,

to looking at insulin resistance, and really one of the true leaders in the air of atherosclerosis

research. So a true honor for us to be able to talk to him and to be able to pick his brain on a

variety of different topics that relate to not only his work, but building off in the back

of several topics we've discussed in previous episodes of the podcast. Now with that said,

this episode does get into quite a lot of the nitty gritty details and can get quite complex at times.

So it might be a good place to start to go back and listen to some previous episodes or to read some of our writing that relates to this topic.

So notably, for example, episode 350 of this podcast might be a good one to also listen to, to get more of the details that we'll build on here.

Or you can check out our Sigma statement that's over on the website.

So we did a series on heart disease risk and part one of that, which was titled cholesterol, lipoproteins, and lipids, understanding cardiovascular disease

risk. That statement in particular will serve a basis for many of the things we may discuss here.

Now, of course, that is all optional. You can listen through today here, of course, but those are

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