370. Microbiomes & Menopause: What’s Really Driving Your Symptoms?

You Are Not Broken

Kelly Casperson, MD

Medicine, Health & Fitness

4.8 • 1.1K Ratings

🗓️ 10 May 2026

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

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Summary

The Gut-Brain-Hormone Connection in Midlife with Cynthia Thurlow - Explore how hormonal shifts, the microbiome, and lifestyle factors intertwine to impact women's health during midlife. Cynthia Thurlow shares insights on gut health, hormone therapy, and debunks common misconceptions. This episode offers practical advice for optimizing wellness through personalized approaches. Key Topics: The emerging importance of the gut microbiome in menopausal health How hormones like estrogen influence colon cancer risk and overall health The role of lifestyle factors (diet, stress, antibiotics) on microbiome integrity Advances in hormone therapy, including the potential for microbiome restoration The impact of medications like GLP-1 agents on inflammation and weight Strategies for improving digestion, stool health, and addressing SIBO The myth of genetics being destiny—hormones as a modifiable factor Predatory practices in vaginal health treatments and how to ensure informed choices The significance of fiber: how to increase it safely and effectively Practical daily habits to support gut motility and overall wellness Menopause Gut Book IG for Cynthia Thurlow, NP Listen to my Tedx Talk: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Why we need adult sex ed⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Take my ⁠⁠⁠⁠⁠⁠⁠Adult Sex Ed Master Class:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠My Website⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Interested in my sexual health and hormone clinic? ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Waitlist is open⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ To learn more about Via vaginal moisturizer from Solv Wellness, visit ⁠⁠⁠via4her.com⁠⁠⁠ and get 20% off your first order. For an additional $5 off, use coupon code DRKELLY5. Clinicians can request patient materials or samples at ⁠⁠⁠hcp.solvwellness.com⁠⁠⁠. Thanks to our sponsor ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Midi Women's Health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠. Designed by midlife experts, delivered by experienced clinicians, covered by insurance.Midi is the first virtual care clinic made exclusively for women 40+. Evidence-based treatments. Personalized midlife care.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.joinmidi.com⁠ Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0	Welcome to You Are Not Broken, the podcast that challenges everything we've been taught about midlife, hormones, and sexuality.
0:10.0	I'm Dr. Kelly Casperson, board certified jurologist, author, and a leading voice in women's sexual and hormone health.
0:15.9	Enjoy the show.
0:17.4	Hey, everybody. Welcome back to the You're Not Broken podcast. Today I have my friend on Cynthia Thurlow,
0:20.9	and we've just been chatting and not hitting record. So now we're going to hit record and talk about
0:24.6	the gut, although other things might come up, such as the perils of book tours, the sexless
0:30.9	lives of menopausal women, and what we all want to do about it. So welcome to the You're Not Broken
0:35.9	podcast. Oh, so good to be here, Kelly.
0:38.4	And as listeners should know, we probably spent 15 minutes unpacking the lives of what happens
0:43.9	during a book tour. They're like, wait, the podcast just started. She didn't hit record. You're in the
0:48.9	middle of book tour for the menopause gut, balance your microbiome, reclaim your health in midlife
0:53.6	and beyond.
0:54.8	The gut's very hot right now.
0:56.6	This couldn't be more timely.
0:58.3	I think five years ago there would have been crickets for this book.
1:01.5	And now it's hot, hot, hot.
1:03.0	Can you give us your overview of like, it's time to write a book about this?
1:07.1	Because it's getting buzzworthy.
1:09.2	Yeah, you know, it's interesting.
1:10.4	This is obviously
1:11.3	content neither you nor I learned about during our medical training because it's really been
1:16.7	the last five to ten years that all this proliferative amount of research has come out.
	...

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