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The Melanie Avalon Biohacking Podcast

#352 - Cynthia Thurlow: The Menopause Gut, The Gut Microbiome Effects, Hormone Replacement Therapy, Ovaries As The Pacemaker Of Aging, Trauma, ACEs & Stress, Intermittent Fasting Problems, SCFAs, Nitric Oxide & Urolithin A, The Effects Of Estrogen, Combatting Inflammaging, Supporting The Immune System, And More!

The Melanie Avalon Biohacking Podcast

Melanie Avalon

Alternative Health, Nutrition, Health & Fitness

4.7655 Ratings

🗓️ 1 May 2026

⏱️ 103 minutes

🧾️ Download transcript

Summary

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Transcript

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0:00.0

It's not like all inflammation is bad.

0:05.0

There's a lot to inflammation that is good that helps protect us.

0:08.0

It's when it goes awry.

0:10.0

And certainly, when it's out of control, it can accelerate the aging process.

0:14.0

Like we do see in middle age and beyond.

0:17.0

Some people will breeze through their 30s and 40s and others will not.

0:28.7

And I think so much of it is really a reflection of what we're doing in our, in terms of lifestyle, how we eat, how we choose to exercise.

0:32.2

Do we have healthy relationships and boundaries or do we not?

0:39.1

Welcome to the Melanie Avalon Biohacking podcast, where we meet the world's top experts to explore the secrets of health, mindset, longevity, and so much more. Are you ready to take charge of your

0:45.0

existence and biohack your life? This show is for you. Please keep in mind. We're not dispensing

0:51.5

medical advice and are not responsible for any outcomes you may

0:55.3

experience from implementing the tactics lying herein. So friends, are you ready to join me?

1:01.3

Let's do this. Welcome back to the Melanie Avalon biohacking podcast. Oh my goodness, friends. What an honor to be back

1:12.4

with a crowd favorite. You guys know her well, most likely. That is my former co-host of the

1:17.9

Interminton Fasting podcast, Cynthia Thurlow, for her incredible new book, The Menopause Gut.

1:24.1

I am so grateful to Cynthia for how deep she is diving into this incredible topic. It is wild,

1:30.9

just how much the gut microbiome plays a role in menopause symptoms and our hormones in general.

1:36.2

We talk about so many things in today's episode, things like why the ovaries are a pacemaker

1:41.5

of aging, the effects of trauma, stress, and adverse childhood events

1:45.8

on the gut microbiome, the benefits of short chain fatty acids, nitric oxide, and uralithin

1:50.7

A, the powerful effects of estrogen, whether or not you should do hormone replacement therapy,

1:56.0

how to support the immune system, problems with intermittent fasting, Yes, Cynthia has changed her perspective a little bit

...

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