307. Doctored - Charles Piller and Fraud in the Quest to Cure Alzheimer's

You Are Not Broken

Kelly Casperson, MD

Medicine, Health & Fitness

5 • 743 Ratings

🗓️ 9 March 2025

⏱️ 53 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

“Demonstrates how some of the most accomplished and elite scientific gatekeepers may have lied, cheated, squandered trust and endangered lives.” —The Wall Street Journal In this episode of the You Are Not Broken podcast, Dr. Kelly Casperson interviews investigative journalist Charles Piller about his newly released book, 'Doctored,' which delves into the misconduct in Alzheimer's research. They discuss the amyloid hypothesis, the role of whistleblowers, the FDA's controversial drug approvals, and the systemic issues in medical research. Piller emphasizes the importance of scientific integrity and the need for independent oversight in research while also exploring emerging theories in Alzheimer's treatment and the impact of lifestyle factors on prevention. Takeaways The amyloid hypothesis has dominated Alzheimer's research but has significant flaws. Whistleblowers play a crucial role in exposing misconduct in scientific research. The FDA's approval process for drugs can be influenced by industry relationships. Lifestyle factors such as diet and exercise can impact Alzheimer's risk. There is a growing interest in alternative theories for Alzheimer's treatment. AI can assist in detecting research fraud but also poses risks for falsification. Misinformation in health media can lead to public harm and confusion. Independent agencies are needed to investigate scientific misconduct effectively. The scientific community must improve transparency and accountability. There is hope for progress in Alzheimer's research despite current challenges. Sedona in October - only a few slots left: https://www.ascendretreats.com/menopause-and-sexual-health-2025 Order my book "You Are Not Broken: Stop "Should-ing" All Over You Sex Life" Listen to my Tedx Talk: Why we need adult sex ed Take my Adult Sex Ed Master Class: My Website Interested in my sexual health and hormone clinic? Starts 2025. Thanks to our sponsor Midi Women's Health. Designed by midlife experts, delivered by experienced clinicians, covered by insurance. Midi is the first virtual care clinic made exclusively for women 40+. Evidence-based treatments. Personalized midlife care. https://www.joinmidi.com Thanks to our sponsor Sprout Pharmaceuticals. To find out if Addyi is right for you, go to addyi.com/notbroken and use code NOTBROKEN for a $10 telemedicine appointment. See Full Prescribing Information and Medication Guide, including Boxed Warning for severe low blood pressure and fainting in certain settings at addyi.com/pi To learn more about Via vaginal moisturizer from Solv Wellness, visit via4her.com for 20% off your first purchase of any product, automatically applied at checkout. For an additional $5 off, use coupon code DRKELLY5. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Transcript

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0:00.0	Did you know that I can prescribe an FDA-approved pill to boost your sex drive, ladies?
0:05.5	Yes, there's an FDA-approved treatment called Addie that is clinically proven to boost libido
0:11.2	in certain premenopausal women bothered by low sex drive. Some call Addie the little pink pill.
0:18.1	You know how passionate I am about your sexual wellness. And I've witnessed
0:22.1	firsthand what treating a woman with Addie can do for her. Speak to your doctor about Addy if you're
0:28.1	struggling. Even talk to a telehealth doctor online today at ADDY.com. You deserve to get your sex drive back.
0:38.6	Addie, or Flavansarin, is for premenopausal women with acquired generalized hypoactive
0:42.2	sexual desire disorder, HSDD, who have not had problems with low sexual desire in the past,
0:46.5	who have low sexual desire no matter the type of sexual activity, the situation, or the sexual
0:50.5	partner. The low sexual desire is troubling to them and is not due to a medical or mental health
0:54.6	problem, problems in the relationship, or medicine or other drug use.
0:57.6	Adi is not for use in men or to enhance sexual performance.
1:00.4	Your risk of severe low blood pressure and fainting is increased if you drink one to two
1:03.7	standard alcoholic drinks close in time to your Adi dose.
1:06.2	Wait at least two hours after drinking before taking Adi at bedtime. Your risk of severe low blood pressure and fainting is also increased if you take certain
1:12.5	prescriptions, over-the-counter or herbal medications, or have liver problems.
1:16.0	Low blood pressure and fainting can happen when you take Adi, even if you don't drink
1:19.2	alcohol or take other medicines.
1:20.6	Do not take if you are allergic to any of the ingredients in Adi.
1:23.3	Allergic reactions may include hives, itching, or trouble breathing. Sleepiness, sometimes serious, can occur.
1:28.1	Common side effects include dizziness, nausea, tiredness, difficulty falling asleep or staying asleep and dry mouth.
1:32.9	See full PI and medication guide, including boxed warning at adi.com slash PI or call 844 pink pill.
	...

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