226. Why NAD3 Crushes NMN & NR (The Truth About Cellular Energy)

The Kris Gethin Podcast

Kris Gethin

Fitness, Health & Fitness, Nutrition

4.9 • 598 Ratings

🗓️ 25 September 2025

⏱️ 18 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

Most NAD+ supplements are fluff. NMN? NR? They're precursors, half the story. In this episode, I break down why NAD3 isn't just another molecule, it's the master key for energy, recovery, and longevity.

We get into the real science: how NAD+ fuels your mitochondria, repairs DNA, activates sirtuins, and slows aging at the cellular level. I explain why levels crash after 40, how stress, toxins, and training hammer your reserves, and why NMN/NR often fail thanks to CD38 and PARP overactivity.

You'll learn why NAD3 bypasses the weak links, how it stacks with spermidine, glutathione, and autophagy activators, and why Regen NAD is the one I actually use daily, because it works.

Forget the hype. This is metabolic firepower that hits. If you're overtrained, under-recovered, or want to stay biologically younger for longer: listen in.

What's Discussed:

[00:30] – What Is NAD+ and Why It's Non-Negotiable
[03:30] – Why Your NAD Levels Plummet After 40
[07:15] – NMN & NR: Overhyped Precursors That Don't Deliver
[09:30] – NAD3: The Smarter, More Effective Upgrade
[11:00] – My Daily NAD Protocol (and Why IVs Suck)

Thank You for Our Sponsors:

NAD + Cell Shield from Biostack Labs https://biostacklabs.com/kris
BiOptimizers - code KRIS10 for 10% off https://bioptimizers.com/
Peptide Flask - Get your here and use KRIS10 is the code for 10% off.

My Go-To for Gut Health:

Glutamine and Imuno-IGG from Unmatched Supplements: https://www.unmatchedsupps.com/collections/digestion-gut-health

Find more from Kris:

Website: https://www.krisgethin.com/
Website:https://www.unmatchedsupps.com

Instagram: @krisgethin

Youtube: https://www.youtube.com/krisgethin
2 Shred: https://www.unmatchedsupps.com/products/2shred

Transcript

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0:00.0	Welcome to the Chris Getten podcast where we dive deep into the science of building a stronger physique,
0:11.9	unlocking the secrets of anti-aging and optimizing your health through cutting edge biohacks,
0:17.6	fitness strategies and mental resilience. I've been a personal trainer for nearly 30 years now and voted the number one transformation
0:25.2	trainer by governing bodies such as PT Academy, bodybuilding.com and trainerize.
0:31.9	I am the co-founder of unmatched supplements, co-founder of the Chris Kathleenethyn Jims franchise, and co-founder of my
0:39.6	online coaching platform, Chris Kethin Coaching, and author of several books. I'm a hybrid athlete,
0:46.2	a natural pro bodybuilder, and I've competed in events such as Iron Man Triathlon, Ultramarathon,
0:52.0	Spartan, and many more. My goal with this podcast is to cut through
0:56.7	the noise of fitness myth, misconceptions, and deliver clear protocols, actual tips, and real
1:04.1	resilience and science to help you optimize your physique, elevate your physical and mental
1:10.4	health span, and, of course, enhance your
1:13.5	life. Welcome to the Chris Getham podcast, everyone. Today, we are going to dive into one of the most
1:22.0	important conversations in longevity, in performance, and in recovery.
1:32.3	And this is the molecule that sits at the very center of your cellular health.
1:38.7	And we're talking about NAD plus, and more specifically, how NAD3, which is a patented ingredient complex, is changing the game for boosting and maintaining NAD plus levels in ways that things like
1:47.6	NMN and NR, these precursors, never can. Now, if you've been following my work, you know that I'm
1:53.7	obsessed with finding strategies that don't just make you fitter and stronger in the short term,
2:00.2	but strategies that extend your health span,
2:02.8	because living longer is meaningless if those extra years are weak, you're fatigued,
2:08.0	you have disease, and you're compromised. Now, the goal is to live better for longer,
2:13.5	with energy, strength, clarity, and resilience. An NAD Plus is at the center of that mission for me personally, and I'm going to explain to you why.
2:22.5	But let's start with the basics.
	...

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