#204 NephMadness 2020: SGLT2 Inhibitors

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 6 April 2020

⏱️ 50 minutes

🔗️ Recording | iTunes | RSS

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Summary

Get under the hood of SGLT2 inhibitors! Listen as our guests Dr. Harish Seethapathy, Dr. Matt Sparks, and Dr. Joel Topf give us a tour through the NephMadness 2020 SGLT2i region! How do these promising drugs work, and what evidence is there for using them in non-diabetic kidney disease or kidney transplant patients. Show Notes | Spotify | Swag! | Top Picks | Mailing List | [email protected]

Credits

Written and Produced by: Hannah R. Abrams
Cover Art and Infographic by: Hannah R. Abrams
Hosts: Hannah R Abrams, Matthew Watto MD, FACP
Editor: Clair Morgan of Nodderly.com (audio), Emi Okamoto MD (written)
Guests: Harish Seethapathy MD; Matthew Sparks MD; Joel Topf MD

Sponsor: McGraw Hill

Time Stamps

00:00 Sponsor
00:26 Intro, disclaimer, guest bio
02:57 Guest one-liner and Picks of the Week*: Michael Pollan audiobook on Coffee and Caffeine Addiction
03:52 SGLT2i definition, background, and why we now consider CV endpoints in diabetes
11:16 Sponsor
12:00 Tubuloglomerular feedback; Balloon analogy
17:40 Other mechanisms for SGLT2i
23:05 Back to the case; Risks from SGLT2i; Counseling and Monitoring
34:18 SGLT2i for non-diabetic kidney disease; Possible mechanisms: Joel’s caution against early adoption
41:42 SGLT2 inhibitors in kidney transplant
45:20 Take home points and picks for the SGLT2 inhibitor region
49:50 Outro

Transcript

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0:00.0	The Curbsiders podcast is for entertainment, education, and information purposes only.
0:07.0	And the topics discussed should not be used solely at Diagnostry, or prevent any diseases
0:09.8	or conditions.
0:10.8	For the more the views and statements expressed on the podcast are solely those of those,
0:12.3	and should not be interpreted to reflect official policy or position of any entity
0:14.5	aside from possibly, cash like Moronsville and affiliate outreach programs.
0:16.9	If indeed there are any, in fact there are none.
0:18.7	Pretty much we aren't responsible if you screw up, you should always do your own homework
0:20.5	and let us know when we're wrong.
0:31.0	Well Hannah, we're here, we're without Stuart and Paul, this is the Curbsiders, we're
0:37.0	going to be talking about SGLT2 inhibitors tonight.
0:39.7	Thank you so much for coming back.
0:41.7	How have you been?
0:42.7	Ah, I am doing great.
0:45.3	I have my last lecture of med school tomorrow, and tonight I got to learn so much about
0:50.0	SGLT2 inhibitors.
0:51.8	They are the team to be for nap madness.
0:53.5	I am convinced.
0:54.5	Okay, tell them, since Paul's not here, you get to do this.
0:58.3	What is it that we do on the show?
0:59.7	Just in case some of these people have never heard it before.
1:02.6	Well Matt, we are the internal medicine podcast.
	...

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