#174 Lp(a) and ASCVD Risk: 5 Pearls Segment

Core IM | Internal Medicine Podcast

Core IM Team

Mental Health, Education, Health & Fitness, Medicine

4.8 • 1K Ratings

🗓️ 2 April 2025

⏱️ 46 minutes

🔗️ Recording | iTunes | RSS

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Summary

What does Lipoprotein(a) tell us that a standard lipid panel doesn’t? Should we be testing everyone for it? Dive into the genetics, clinical implications, and evolving management strategies for Lp(a). Learn how to interpret results, counsel patients, and navigate topics with limited data like aspirin and PCSK9 inhibitors in treatment.

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🔹 Transcript and Show Notes

Timestamps:

(02:17) | Pearl 1: What makes Lp(a) unique? How does it raise ASCVD risk?

(10:32) | Pearl 2: Who should be tested for Lp(a)? When and why?

(16:54) | Pearl 3: Understanding and interpreting Lp(a) levels

(24:04) | Pearl 4: How does an elevated Lp(a) affect management?

(37:05)| Pearl 5: The role of aspirin and PCSK9 inhibitors in Lp(a)

Tags: CoreIM, Internal Medicine, Primary Care, Preventive Cardiology, Atherosclerosis, Lipid Management, Medical Education, IMCore, Physician Assistant, Nurse Practitioner, Medical Student

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Transcript

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0:00.0	A quick word from our sponsor, Freed. If you're looking to streamline your workflow,
0:04.3	Freed is an AI scribe designed to help you do just that. Freed will listen, transcribe, and
0:09.7	draft your note all the while being fully HIPAA compliant. I've been using Freed regularly
0:15.6	on my shifts and I do have to say it is really user-friendly. It seamlessly integrates into my workflow on the phone
0:22.2	and on the computer. I've also really appreciated how it really adapts to my style of note writing.
0:27.6	I think we all have our unique ways we like our notes to be. For what it's worth, I think can be
0:32.4	a huge game changer in making all our days feel a bit more manageable. And you can also use the code Core 50 to get $50 off your first month of Freed.
0:42.2	Again, that's Core 50 for $50 off your first month of Freed.
0:46.6	So give it a try and see how an AI scribe can make a difference in your day.
0:51.4	And with that, let's get into the episode.
0:54.0	Knowledge is power. Everybody needs to know what their life or protein A level is, including
1:00.1	both of you. And if you don't know what your life or protein A level is, find out. You might
1:06.0	get a big surprise. And knowing that you have a risk factor is important.
1:11.7	Welcome to the Corian Thai Five Pearls podcast. Bring you high-yield evidence-based pearls.
1:17.4	I'm Dr. Shraya Chavetti and I'm joined by Dr. Ian Kelly, a resident at BIDMC. Today we are talking
1:23.3	all things L.P. Little A. You know, Shreya, when I first read about L.P. Little A, I never knew how it was
1:29.2	pronounced. I cycled through a mumbled lipoprotein level A or just lipoprotein A under my breath
1:35.0	until starting an interview for this episode and mercifully being informed by our first expert
1:40.0	that it was in fact known as LP. Little A.
1:45.6	It is so humbling.
1:49.2	It is not intuitive when you read it, so I definitely was there with you.
1:54.3	All right, before we get started, let's take a moment and challenge yourself on the following questions.
	...

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