#168 - Morgan Levine: True Age, The Science Of Aging, Female Longevity Advantage, Epigenetic Reprogramming, Plasma Exchange, Yamanaka Factors, Biological Age Vs Chronological Age, And More!

The Melanie Avalon Biohacking Podcast

Melanie Avalon

Alternative Health, Nutrition, Health & Fitness

4.5 • 650 Ratings

🗓️ 21 October 2022

⏱️ 105 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/morganlevine 2:00 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 11:00 - Morgan's Background 14:15 - Why Do We Age? 16:30 - Aging In The Animal Kingdom 18:15 - Child Bearing And Longevity 20:00 - Communal Child Rearing 21:45 - The Biological Drive To Continue The Species 23:05 - Cancer Immortality 25:00 - Senescent Cells 27:45 - Biological Aging 29:00 - What Is Aging? 36:45 - Where Does The Aging Process Start? 39:30 - Comorbidities With Age 41:00 - Super-Centennarians 42:25 - Can We Edit Our Genes To Live Longer? 45:30 - Phenotypes Of Aging 50:20 - Defining Biological Age 51:20 - Are We Aging Faster Than Before? 53:30 - Disease Processes 55:00 - When Does Aging Actually Start 56:30 - Measuring Biological Age 58:00 - DNA Methylation 59:30 - The 9 Biomarkers To Tell Your Biological Age 1:02:25 - Historical Data Of Chronic Diseases 1:05:30 - Methylation Status As Compared To Health 1:06:50 - Epigenetic Clocks 1:14:10 - Can We Change Our Methylation? 1:17:35 - Yamanaka Factors 1:20:10 - Can We Make Changes To Our Yamanaka Factors? 1:23:25 - Can Our Genome Age Backwards? 1:24:50 - Testing Yamanaka Factors 1:26:15 - What Is The Most Practical In Anti-Aging? 1:27:35 - Plasma Exchange 1:31:35 - Rapamyicin 1:32:20 - Morgan's Practical Implimentations 1:33:50 - How Fast Can We See Changes If We Change Our Lifestyles? 1:36:30 - Consumer Products For Testing Inner Age 1:37:20 - NR And NMN 1:38:15 - The Future Of Anti-Aging 1:41:30 - How Intuitive Are We? 1:45:10 - Guessing Ages

Transcript

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0:00.0	That's why I think with age, we tend to see this increase in what we call comorbidities.
0:06.0	More and more cells can actually transition to the senescent state at a faster rate in people who might be aging faster.
0:12.0	Traits like longevity tend to have lots and lots and lots of genes that are all acting simultaneously. So how do we target those pathways?
0:23.4	These super centenarians tend to have kind of won the genetic lottery.
0:27.9	So they have kind of the perfect permutation of genetic variants.
0:31.6	Welcome to the Melanie Avalon Biohacking Podcast, where we meet the world's top experts to explore the secrets of health,
0:40.2	mindset, longevity, and so much more. Are you ready to take charge of your existence and biohack
0:47.1	your life? This show is for you. Please keep in mind, we're not dispensing medical advice
0:52.9	and are not responsible for any outcomes you may
0:55.7	experience from implementing the tactics lying here in are you ready let's do this
1:03.9	welcome back to the melanie avalon biohacking podcast oh my goodness friends i am so excited about today's episode. I was hearing Morgan Levine
1:13.6	on all of the podcast. She is such a well-respected figure in the world of longevity science.
1:19.4	I knew I had to book her. And then when her people reached out to me about coming on the show,
1:23.8	it was just an automatic yes. This interview turned out to be everything I could want
1:28.6	and more. We dive so deep into so many topics, like the difference between your biological
1:34.0	and chronological age and what affects that, how we can actually reset ourselves to a younger
1:39.7	state. Even things like plasma and blood transfusions, You do not want to miss this episode, and I
1:45.5	can't wait to hear what you guys think. The show notes for today's episode will be at
1:48.9	Melanieavalon.com slash Morgan Levine. That's M-O-R-G-A-N-L-E-V-I-N-E. Those show notes will
1:56.8	have a full transcript, so definitely check that out. There will be two giveaways for this episode.
2:01.6	One will be in my Facebook group, I have biohackers, intermittent fasting plus real foods plus life.
2:06.5	Comment something you learned or something that resonated with you on the pinned post to
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