153: Xenotransplants: The Man With a Pig Heart

Sci Guys

The Sci Guys

Science, Comedy, Education

4.9 • 632 Ratings

🗓️ 21 March 2022

⏱️ 79 minutes

🔗️ Recording | iTunes | RSS

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Summary

Human organs are in short supply - but this year scientists decided to genetically modify a pig heart to save the life of a man with terminal heart disease. This xentoransplant is brand new science & had never been done before. This week we go over the crazy experiments and mind-blowing science that led to this medical marvel.

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References & Further Reading

Xenotransplantation
https://archive.bio.org/articles/xenotransplantation-benefits-and-risks-special-organ-transplantation
https://www.omixon.com/brief-history-xenotransplantation/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684730/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246856/
https://www.who.int/ethics/en/ETH_Nuffiled_xenotransplantation.pdf
https://www.frontiersin.org/articles/10.3389/fimmu.2019.03060/full
https://www.fda.gov/vaccines-blood-biologics/xenotransplantation
https://www.groomers-online.com/professional-c1/scissors-c22/left-handed-scissors-c265/groomers-elite-45-straight-left-handed-bull-nosed-scissors-p755
https://pubmed.ncbi.nlm.nih.gov/34697231/

Organ Donation & Transplants
https://www.organdonation.nhs.uk/helping-you-to-decide/about-organ-donation/statistics-about-organ-donation/
https://www.organdonation.nhs.uk/helping-you-to-decide/about-organ-donation/living-donation/
https://www.nhsbt.nhs.uk/what-we-do/transplantation-services/organ-donation-and-transplantation/

First Pig Heart Transplant
https://www.economist.com/science-and-technology/2022/01/15/the-science-behind-the-first-successful-pig-to-human-heart-transplant
https://www.bbc.co.uk/news/world-us-canada-59944889.amp
https://www.nature.com/articles/d41586-022-00111-9
https://secure.jbs.elsevierhealth.com/action/consumeSsoCookie?redirectUri=https%3A%2F%2Fwww.thelancet.com%2Faction%2FconsumeSharedSessionAction%3FJSESSIONID%3DaaaBetSmryb39fIGYw37x%26MAID%3DcerwNnXJRoDD37sdGKDXfw%253D%253D%26SERVER%3DWZ6myaEXBLFD8VbcQEfOcg%253D%253D%26I2KBRCK%3D1%26ORIGIN%3D695817921%26RD%3DRD%26exp%3DTEn4cY9Dbt214rWTophWGQ%25253D%25253D&code=null&acw=Secure;SameSite=None&utt=
https://amp.theguardian.com/science/2022/feb/03/german-researchers-to-breed-pigs-for-human-heart-transplants

Transcript

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0:00.0	Hello and welcome to the Sci guys, the show where we talk about the crazy, weird and wonderful stories from the science world.
0:12.8	I'm Corey, and as always, I'm joined by my co-hosts, Jem and Luke Cutterford.
0:17.0	Hi, hi, howdy. This week we're talking about GMO tickers and pork pumps.
0:31.6	Gee?
0:32.6	Ooh.
0:33.6	But first, why don't we look at a little Apple review?
0:36.6	Okay. So this one comes from Angry Face K. It is, I know, but it's five stars.
0:42.3	I've just checked, actually, our Apple score, our Apple, like, thing, it's five out of five
0:47.3	stars. It's been on 4.9 for so long. We've hit five stars.
0:50.3	Very good.
0:51.3	Because you guys have been leaving so many five star reviews, which is awesome. Please leave some more and we'll read them out on the show.
0:55.0	So this one says, absolutely fantastic podcast, a perfect mix of actual science and dumb conversations.
1:00.7	It's currently my favorite podcast, and I would recommend it to anyone wanting to learn about science in a more interesting way.
1:07.3	Oh, that is so nice. I also think that Angry Face K might be a more discerning person on average, and yet
1:14.4	we have impressed her.
1:15.4	That's lovely.
1:16.4	Well, you assume it's a her?
1:18.4	Angry face?
1:19.4	K.
1:20.4	Okay, as in the letter K.
1:21.4	Oh, I thought it was the name K.
1:23.0	Nope.
	...

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