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The Melanie Avalon Biohacking Podcast

#141 - Dr. David Perlmutter: Drop Uric Acid, The Cause Of Metabolic Syndrome, Salt & Obesity, Alcohol, Purines & Gout, Mitochondrial Dysfunction, Endogenous Fructose Production, High Blood Sugar & Blood Pressure, And More!

The Melanie Avalon Biohacking Podcast

Melanie Avalon

Alternative Health, Nutrition, Health & Fitness

4.5650 Ratings

🗓️ 15 April 2022

⏱️ 76 minutes

🧾️ Download transcript

Summary

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/uricacid 2:15 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:15 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon 11:45 - Why Does Fructose Threaten Our Health? 13:50 - Can We Evolve Out Of The Obesity Signaling Pathway From Fructose? 20:20 - Triggering The Pathway 21:20 - Orange Juice 23:55 - The Historical Consumption Of Fructose 25:45 - Depletion Of Energy In The Cell By Fructose Metabolism 30:15 - AMPD 34:05 - Neurological Effects Of High Uric Acid 36:00 - Uric Acid's Role As An Independent Risk Factor In Mortality 40:50 - Does Metabolic Syndrome Come With High Uric Acid Exclusively 41:40 - Purines 46:00 - Checking Uric Acid 47:20 - "Normal Levels" 48:30 - Recommended Sugar Consumption Per Day 52:00 - Allopurinol  54:45 - Does Ketosis Create Uric Acid? 1:00:10 - Cycling Keto 1:03:30 - Healthy Mitochondria 1:06:00 - Gender And Uric Acid 1:09:20 - Endogenous Fructose Production 1:11:15 - Why Is The Body Making Fat If It Feels Its Dehydrated? 1:13:30 - The Evolution Of Storing Fat For Metabolic Water 1:15:00 - Sodium In The Diet 1:16:15 - Drugs That Elevate Uric Acid 1:17:40 - Quercetin Daily

Transcript

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0:00.0

Fructose signal the body through increasing uric acid to make and store fat.

0:08.0

And it happens to help keep us humans alive, giving us the ability to survive when we didn't have access to food or water.

0:16.0

We're going in the wrong direction.

0:18.0

And so what we're talking about here is basically a mismatch

0:21.6

between our genetics that have been refined over literally millions of years

0:26.9

and the influences on our physiology brought on by our environment.

0:31.3

Welcome to the Melanie Avalon Biohacking Podcast,

0:34.8

where we meet the world's top experts to explore the secrets of health,

0:40.2

mindset, longevity, and so much more. Are you ready to take charge of your existence and biohack

0:47.1

your life? This show is for you. Please keep in mind. We're not dispensing medical advice

0:52.9

and are not responsible for any outcomes you may

0:55.7

experience from implementing the tactics lying herein. Are you ready? Let's do this.

1:04.0

Welcome back to the Melanie Avalon Biohacking Podcast. Friends, I am so excited about today's

1:10.2

episode. It is a surreal one. I always am just so in awe

1:15.2

when I get to interview people that I have been looking up to for so, so long. And not only that,

1:21.2

the fact that this is actually my second episode with Dr. Perlmutter is just so incredible.

1:27.3

I am so so grateful. And the topic is one that I am

1:30.6

becoming increasingly more and more interested in. And that is the role of fructose and uric acid in

1:37.6

our metabolic health. I recently interviewed Dr. Rick Johnson for his book, Nature Wants Us to Be Fat.

1:43.6

I haven't aired that episode yet, but that is the first

1:46.2

book that really got me interested in this topic. And then when I saw Dr. Perlmander's book, I was so,

1:51.2

so excited to dive even deeper into Yark Acid. Having him on the show was incredible. He is so

...

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