#1220 Microplastics Are Wrecking Your Metabolism - The Shocking Detox Science You Need to Know with David Roberts and Dr. John Gildea

The Ben Azadi Show

Ben Azadi

Nutrition, Fitness, Health & Fitness, Alternative Health

4.8 • 1.1K Ratings

🗓️ 19 January 2026

⏱️ 54 minutes

🔗️ Recording | iTunes | RSS

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Summary

What if the biggest metabolism disruptor today is not carbs or calories, but the toxic load you cannot see? In this episode of the Metabolic Freedom Podcast, Ben Azadi sits down with Mara Labs co-founders David Roberts and Dr. John Gildea for a deep dive into microplastics, detox pathways, and the science of sulforaphane. They break down how microplastics and the chemicals that leach from plastics can interfere with cellular function, including lysosomes, autophagy, inflammation, and hormone signaling. You will learn why sulforaphane is known for activating Nrf2, what that means for detox and repair genes, and why the conversation around metabolic health is also a conversation about toxin exposure. They also discuss berberine as a tool for metabolic flexibility, blood sugar support, ketosis, and even sleep, plus new product innovations like BarkElite for dogs. If you want practical strategies backed by research and real-world testing, this one is packed. Key Topics Covered Why microplastics are everywhere and why that matters for metabolism and longevity How microplastics may interfere with lysosomes, autophagy, and cellular cleanup What sulforaphane is and how it activates the Nrf2 pathway Phase 1, 2, and 3 detox explained in plain English Why inflammation is often the real root issue behind stubborn fat loss Berberine, AMPK, GLP-1 signaling, and metabolic flexibility Why late-night eating can wreck sleep and HRV The dog angle: joint support, inflammation, and BarkElite Coupon and Discount Browse all products featured in this episode : http://www.benazadi.com/mara Mara Labs discount code: FREEDOM 25% off from January 19, 2026 through January 26, 2026 After January 26, 2026: code still works for 15% off Follow Ben Azadi 🌐 Website:⁠⁠⁠ https://www.benazadi.com ⁠⁠⁠ 📸 Instagram:⁠⁠⁠ https://www.instagram.com/thebenazadi ⁠⁠⁠ 💼 LinkedIn:⁠⁠⁠ https://www.linkedin.com/in/benazadi ⁠⁠⁠ 🔎 Find All Metabolic Freedom Sponsorship Deals ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.ketokamp.com/sponsorship-deals Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	When you think about these big pillars of things that push back on longevity and health, if you read enough papers on chronic disease, you realize that NRF2 and AMP kinase and NFCAPAB, those three show up virtually everywhere.
0:30.6	The Greek definition of metabolism means to transform.
0:33.3	Your metabolism isn't broken.
0:39.5	It was designed to take food and transform it into energy, clarity, and fat loss.
0:43.0	So you can feel good in your body and strong in your life.
0:48.0	Here on this podcast, we deliver both the science and art of metabolism.
0:54.0	We sit down with the world's leading experts and thought leaders to have life-changing conversation so you can stop guessing,
0:56.0	start applying, and finally upgrade your metabolism. We dive into topics like fat loss,
1:02.3	metabolic health, fasting strategies, ketosis, carnivore, biohacking and mindset. Because lasting transformation
1:09.7	doesn't come from willpower. It comes from
1:12.6	understanding how your body actually works. Your body was built to be self-healing and fat burning.
1:19.5	When the right signals are present, your metabolism knows exactly what to do. Our mission is
1:25.1	simple. Identify the interference and remove it because when the
1:29.1	interference is gone, fat loss becomes natural, energy returns, and health follows. You are a
1:35.8	masterpiece because you are a piece of the master. Welcome to the Metabolic Freedom podcast.
1:41.9	My name is Benazotti. I'm the New York Times bestselling author of Metabolic Freedom, and I want to thank you for spending part of your day with me.
1:53.7	Hey, welcome back to the Metabolic Freedom Podcast.
1:56.4	I'm your host, Ben Azadi.
1:57.8	You can learn more about me over at Benazadi.com. Today's episode is all about
2:03.0	microplastics. Ooh, these toxins, they're hiding in your blood, your brain, your arteries,
2:09.7	and what do they actually do inside the body and how do you get rid of them? So I'm sitting down
2:15.2	in today's episode with David Roberts and Dr. John Gildia,
	...

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