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The Melanie Avalon Biohacking Podcast

#112 - Dr. John Lieurance: Melatonin The Miracle Molecule, Effective Supplementation, Circadian Rhythms, Inflammation Reduction, Tolerance & Toxicity, Mitochondrial Biogenesis, And More!

The Melanie Avalon Biohacking Podcast

Melanie Avalon

Alternative Health, Nutrition, Health & Fitness

4.5650 Ratings

🗓️ 23 September 2021

⏱️ 91 minutes

🧾️ Download transcript

Summary

GET TRANSCRIPT AND FULL SHOWNOTES: melanieavalon.com/melatonin Go To melanieavalon.com/melatoninbook To Get The Free PDF Download And Use The Code Melanieavalon To Get 5% Off Any Products! 2:40 - IF Biohackers: Intermittent Fasting + Real Foods + Life: Join Melanie's Facebook Group At Facebook.com/groups/paleoOMAD For A Weekly Episode GIVEAWAY, And To Discuss And Learn About All Things Biohacking! All Conversations Welcome! 2:55 - Follow Melanie On Instagram To See The Latest Moments, Products, And #AllTheThings! @MelanieAvalon Stay Up To Date With All The News And Pre-Order Info About Melanie's New Serrapeptase Supplement At melanieavalon.com/serrapeptase! 11:20 - Dr. Lieurance's Personal Story 13:05 - Pain To Purpose 14:30 - Inflammation In All Disease 16:25 - The Signs In The Heart And The Brain 17:00 - Aerobic Glycolysis 18:00 - The Warburg Effect 18:45 - Cancer 21:00 - Genetics Related To Detox 23:55 - The Role Of Melatonin In Inflammation 27:45 - Are There Different Types Of Melatonin? 29:45 - Exogenous Melatonin 31:05 - Suppositories 32:30 - Melatonin Circadian Rhythms 34:00 - Using Red Light In The Evening 35:20 - Cellular Melatonin 38:35 - Heart Rate Variability 41:15 - Melatonin Dosing 41:45 - The Master Stress Hormone 43:00 - Intracellular Melatonin 44:25 - Melatonin And Sleepiness 45:30 - Wi-Fi Go To melanieavalon.com/melatoninbook To Get The Free PDF Download! 47:25 - The Lack Of Discussion Around Melatonin 49:25 - Microbiome Swarming 50:25 - The Rhythm In The Microbiome During Sleep 51:20 - Reduction Of HCL 51:40 - The Inverse Relationship Of Insulin & Melatonin 54:05 - A Short Fast Before Bed 54:30 - Chronotypes 55:35 - Insomniac Types 59:00 - The Half-Life Of Melatonin 1:00:05 - Typical Dosing 1:00:25 - High Exogenous Dosing Effect On Endogenous Production 1:01:35 - Toxicity & Tolerance 1:02:40 - Suppressive Efforts 1:03:45 - Vitamin D; OTC Regulation 1:04:05 - Blood Pressure Medication And Blood Pressure Lowering Effect 1:09:05 - Suppositorial Dosing 1:11:25 - Senescent Cells 1:13:35 - Fisetin & Polyphenols 1:14:10 - Mitophagy 1:14:55 - Mitochondrial Biogenesis 1:17:25 - Prevention Of Skin Burns 1:19:00 - Anti-Inflammatory Effect 1:20:10 - Using Binders For Detox 1:20:50 - Biotoxins & Mold 1:21:50 - Side Effects

Transcript

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0:00.0

The problem with all diseases is that it's rooted with inflammation.

0:04.0

And we know that inflammation shows up as cytokines.

0:08.0

What the cytokines do is they create stress to the cell.

0:12.0

What's the cause of that?

0:14.0

And, you know, toxins and infections are almost always at the cause of that.

0:18.0

These toxins, they settle in the cell membranes.

0:21.5

And this is where all of our hormones are being interpreted.

0:24.6

It's really where melatonin shines as it helps us to be more resilient and adaptable

0:29.3

stress at the mitochondrial level.

0:31.3

Welcome to the Melanie Avalon Biohacking Podcast, where we meet the world's top experts to explore the secrets of health,

0:40.2

mindset, longevity, and so much more. Are you ready to take charge of your existence and biohack

0:47.1

your life? This show is for you. Please keep in mind. We're not dispensing medical advice

0:52.9

and are not responsible for any outcomes you may

0:55.7

experience from implementing the tactics lying herein. Are you ready? Let's do this.

1:04.0

Welcome back to the Melanie Avalon Biohacking Podcast. Friends, I am so excited about today's

1:10.2

episode. It is pretty mind-blowing.

1:13.8

Today's topic is one of those things that I thought I knew about and that I read more and realized

1:21.0

how I had no idea what all was going on with this compound. When you hear melatonin,

1:27.3

if you're like me, you probably

1:28.7

think sleep hormone, and it probably ends there. Well, it does not in there. Dr. John Laurent's book

1:35.2

is almost overwhelming in all of the information it has about melatonin. Who knew this miracle molecule

1:41.3

could do so many things? On top of that, he's just into all the things

...

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