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The Times Tech Podcast

10x Genomics’ Serge Saxonov: "Never has so much brainpower been focussed on one problem"

The Times Tech Podcast

Will Morley

Business, Unknown, Technology

4.9654 Ratings

🗓️ 10 April 2020

⏱️ 36 minutes

🧾️ Download transcript

Summary

The Sunday Times’ tech correspondent Danny Fortson brings on Serge Saxonov, founder of 10x Genomics, to talk about the end of normalcy (3:00), his high-end espresso machine for biology (4:20), delivering on the promise of genomics (6:20), how 10x is contributing to the coronavirus vaccine race (8:00), why a vaccine is theoretically achievable (10:15), the global shift to Covid research (13:15), leaving the Soviet Union and landing in New York (15:30), starting 23andMe (19:20), starting 10x (22:00), why it was hard to raise money (23:25), luring Softbank as an investor (25:55), 10x's footprint (26:50), the importance of resolution (28:10), and his worst day of work (32:00)

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Transcript

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0:00.0

Yeah, technology. What is it all about?

0:04.0

No time in history has anyone had access to these kinds of technologies to understand the biology at that level that we can do now.

0:10.0

That's a huge, huge difference maker.

0:13.0

And so that's one of the ways that certainly our tools are being used to others as well.

0:16.0

Like when you're generating a vaccine, what kind of effect is having on the patient on their biology, on their immune system. And so we can see this at a level that we just could

0:25.5

not even contemplate even a few years ago.

0:32.8

Hello and welcome to Danny in the Valley, your weekly dispatch from behind the scenes and

0:37.4

inside the minds of the top people in tech.

0:40.5

I am your host, Danny Fortson, the West Coast correspondent for the Sunday Times,

0:44.5

and I am back from my quote-unquote holiday, sheltering place here in my house in Oakland.

0:53.2

Can't say it was the most relaxing or restful

0:57.4

vacation, but we're all healthy, so I'm going to still count it as a win. And now we're back

1:04.1

with another podcast. And depending on how the next day goes, this will hopefully be the first

1:10.2

of two episodes headed your way in the next few days.

1:13.9

So just keep your eye on the feed.

1:16.5

On this pod, though, we have a very interesting guest.

1:20.7

Serge Saxonov.

1:22.9

He is an entrepreneur who fled the Soviet Union as it collapsed.

1:29.9

He ended up in New York. And these days he runs 10x Genomics, a maker of a very powerful machine that allows researchers to see down

1:38.3

to the single cellular level. And if you don't know what that really means, it's fine. I didn't really either. But Saxonov is very good at explaining why this is a big deal, especially as we race to find a vaccine for COVID-19. So 10x machines are being used around the world in labs who are dissecting the virus, trying to figure out how

2:01.4

it works, and that's how we might try to attack it.

2:03.7

So you can think of their machines, I'm just making this up, but think of it like if you saw

...

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