In this episode, Dr. Ruscio breaks down the surprising gut and systemic benefits of NAC (N-acetylcysteine), including how it may help break down biofilms, support SIBO and H. pylori treatment, improve gut lining repair, boost nutrient absorption, and support glutathione, mitochondria, and brain health. You'll also learn when sustained-release NAC may be useful, how to dose NAC properly, and what side effects or cautions to keep in mind.

 

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💊 Featured Products:

Biota Dissolve: https://store.drruscio.com/products/biota-dissolve

Jarrow Formulas N-A-C Sustain 600 mg: https://www.amazon.com/Jarrow-Formulas-Sustain-Supports-Function/dp/B0013OVVK0/

 

👇 Watch more videos like this 👇 

➡️ Cure SIBO FASTER (New Research):

https://www.youtube.com/watch?v=u8MsOY5rgAU

➡️ 5 Reasons You Need Glutathione & How To Boost It:

https://www.youtube.com/watch?v=7k7YT70MnA4

➡️ 8 Ways to Beat Brain Fog & Boost Your Cognition: 

https://www.youtube.com/watch?v=Tk_ICGk0RwQ

➡️ Butyrate – The SIBO Treatment Nobody Talks About: 

https://www.youtube.com/watch?v=5B4l1yOn9UA

 

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And if you have any questions or topics you would like covered in the future, let me know in the comments!

 

👇 Read these next 👇

➡️ SIBO Biofilm Explained: Symptoms, Causes, and a Treatment Protocol:

https://drruscio.com/sibo-biofilm/

➡️ What are Biofilms?: https://drruscio.com/biofilms/

➡️ The Best Glutathione Foods (and When to Supplement):

https://drruscio.com/glutathione-foods/

➡️ 8 Best Microbiome Supplements for a Happier, Healthier Gut:

https://drruscio.com/best-microbiome-supplements/

 

📌 Timestamps

00:00 What is NAC?

01:47 H. pylori

04:50 SIBO & biofilms

11:00 Gut lining & nutrient absorption

15:22 IBD

18:18 Systemic benefits

24:16 Gut health protocol

26:14 Systemic protocol

27:29 Side effects

 

Supplementary endoscopy video reproduced from: Baumgartner M, Lang M, Holley H, et al. Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis. Gastroenterology (2021). Available on PubMed Central. Licensed under CC BY 4.0. 

Source: https://pmc.ncbi.nlm.nih.gov/articles/PMC8527885/ 

License: https://creativecommons.org/licenses/by/4.0/ 

Changes: trimmed

 

🎧 Audio Episode & Featured Studies 

📉 N-acetylcysteine and intestinal health: https://pubmed.ncbi.nlm.nih.gov/25553484/

📉 Biofilm demolition and antibiotic treatment to eradicate resistant Helicobacter pylori:

https://pubmed.ncbi.nlm.nih.gov/20478402/

📉 N-acetylcysteine as an adjuvant therapy for Helicobacter pylori eradication: https://pubmed.ncbi.nlm.nih.gov/30746681/

📉 N-acetylcysteine as powerful molecule to destroy bacterial biofilms:

https://pubmed.ncbi.nlm.nih.gov/25339490/

📉 Mucosal Biofilms Are an Endoscopic Feature of Irritable Bowel Syndrome and Ulcerative Colitis:

https://pubmed.ncbi.nlm.nih.gov/34146566/

📉 Low dose rifaximin combined with N-acetylcysteine is superior to rifaximin alone in a rat model of IBS-D:

https://pubmed.ncbi.nlm.nih.gov/39103611/

📉 Biofilm Disruption Enhances Antimicrobial Therapy for Small Intestinal Bacterial Overgrowth and Intestinal Methanogen Overgrowth: https://pubmed.ncbi.nlm.nih.gov/41394228/

📉 Effect of N-acetylcysteine on remission maintenance in patients with ulcerative colitis: https://pubmed.ncbi.nlm.nih.gov/33067169/

📉 Glycine and N-acetylcysteine (GlyNAC) supplementation in older adults improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, insulin resistance, endothelial dysfunction, genotoxicity, muscle strength, and cognition: https://pubmed.ncbi.nlm.nih.gov/33783984/

📉 N-Acetylcysteine Supplementation Elevates Human Brain Glutathione In Vivo: https://cds.ismrm.org/protected/17MProceedings/PDFfiles/4553.html?utm_

📉 Treatment effects of N-acetyl cysteine on resting-state functional MRI and cognitive performance in patients with chronic mild traumatic brain injury: https://pubmed.ncbi.nlm.nih.gov/38299014/

📉 Clinical trials of N-acetylcysteine in psychiatry and neurology: https://pubmed.ncbi.nlm.nih.gov/25957927/

📉 Influence of N-Acetylcysteine Supplementation on Physical Performance and Laboratory Biomarkers in Adult Males: https://pubmed.ncbi.nlm.nih.gov/37299425/

📉 COVID-19 clinical outcomes and N-acetylcysteine (CoViNAC study): https://pubmed.ncbi.nlm.nih.gov/40418545/

📉 Sinus Irrigation with N-Acetylcysteine after Endoscopic Sinus Surgery for Chronic Rhinosinusitis:https://pubmed.ncbi.nlm.nih.gov/39125554/

📉 The effects of N-acetylcysteine supplement on metabolic parameters in women with polycystic ovary syndrome: https://pubmed.ncbi.nlm.nih.gov/37841396/

📉 The role of N-acetyl-cysteine (NAC) orally daily on the sperm parameters and serum hormones in idiopathic infertile men: https://pubmed.ncbi.nlm.nih.gov/33405232/

📉 Anti-Inflammatory and Anti-Oxidant Properties of N-Acetylcysteine:https://pubmed.ncbi.nlm.nih.gov/39064168/

 

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g 

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.