In this video, Dr. Ruscio discusses 8 benefits of taking butyrate, a fat molecule with gut and systemic healing properties. Butyrate is produced by gut bacteria, but it is often low in different chronic health conditions. Supplementation has been shown to improve a variety of gut conditions, including IBS, IBD, and SIBO, as well as chronic inflammation and brain health. Doctor Ruscio also discusses some simple dietary strategies to increase butyrate production naturally. 

 

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💊 Featured Products:

Apollo's Hegemony Microencapsulated Sodium Butyrate: https://www.amazon.com/Butyrate-Butyric-Capsules-Supplement-Support/dp/B0FR9K154Y

BodyBio Sodium Butyrate: https://www.amazon.com/BodyBio-Sodium-Butyrate-Postbiotic-Microbiome/dp/B0058A9SF0/

Tributyrin-Max:

https://www.amazon.com/PERFECT-STOOL-Tributyrin-Max-Postbiotic-Supplement/dp/B0BTQQSXNH/

 

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And if you have any questions or topics you would like covered in the future, let me know in the comments!

 

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📌 Timestamps

 

00:00 What is Butyrate?

01:57 Leaky Gut

04:10 SIBO

06:35 Systemic Inflammation & Immunomodulation

07:59 Weight Loss

09:31 IBS-C & IBS-D

10:53 Inflammatory Bowel Disease

13:10 Diverticulosis

14:00 Traveler's Diarrhea

14:42 Brain Health

16:49 Best Forms

17:19 Best Products

18:45 Dosage & Protocol

19:18 Safety & Side Effects

19:57 Foods To Raise Butyrate Levels Naturally

🎧 Audio Episode & Featured Studies 

📉 Beyond the Gut: Unveiling Butyrate's Global Health Impact Through Gut Health and Dysbiosis-Related Conditions: https://pubmed.ncbi.nlm.nih.gov/40284169/

📉 Acute effects of butyrate on intestinal permeability in patients with irritable bowel syndrome assessed by a novel colonoscopy research model: https://pubmed.ncbi.nlm.nih.gov/40810534/

📉 Butyrate improves handgrip strength and physical performance by reducing intestinal leak in post-menopausal women, a randomized controlled trial: https://pubmed.ncbi.nlm.nih.gov/40167641/

📉 Short-chain fatty acids in the small-bowel bacterial overgrowth syndrome: https://pubmed.ncbi.nlm.nih.gov/4023615/

📉 Effect of microencapsulated sodium butyrate on abdominal symptoms and carbohydrate metabolism in patients with type 2 diabetes: https://www.nature.com/articles/s41598-026-47309-9

📉 The effectiveness of microencapsulated sodium butyrate at reducing symptoms in patients with irritable bowel syndrome: https://pubmed.ncbi.nlm.nih.gov/35371361/

📉 Efficacy of Microencapsulated Sodium Butyrate as Add-On Therapy in Inducing Remission in Patients with Mild-To-Moderate Ulcerative Colitis: https://pubmed.ncbi.nlm.nih.gov/41422374/

📉 Impact of oral butyrate on clinical and biochemical parameters in IBD: https://pubmed.ncbi.nlm.nih.gov/41354580/

📉 The Usefulness of Microencapsulated Sodium Butyrate Add-On Therapy in Maintaining Remission in Patients with Ulcerative Colitis: https://pubmed.ncbi.nlm.nih.gov/33291846/

📉 The Effect of Sodium Butyrate Enemas Compared with Placebo on Disease Activity, Endoscopic Scores, and Histological and Inflammatory Parameters in Inflammatory Bowel Diseases: https://pubmed.ncbi.nlm.nih.gov/33352566/

📉 Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis—a prospective randomized study: https://link.springer.com/article/10.1007/s00384-013-1807-5

📉 Micro-encapsulated and colonic-release sodium butyrate modulates gut microbiota and improves abdominal pain in patients with symptomatic uncomplicated diverticular disease: https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2025.1487892/full

📉 Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea:

https://www.sciencedirect.com/science/article/abs/pii/S1477893913001373?via%3Dihub

📉 A Novel Butyrate Generator Helps Modulate the Gut-Brain Axis: https://www.dovepress.com/article/download/109943

📉 Dietary tributyrin supplementation in Parkinson's disease: https://pubmed.ncbi.nlm.nih.gov/41271518/

 

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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.

Music featured in this video: "Modern Technology" by Andrew G, https://audiojungle.net/user/andrew_g 

*Full transcript available on YouTube by clicking the "Show transcript" button on the bottom right of the video.