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The Human Upgrade: Biohacking for Longevity & Performance

10 Minute Weekly Biohacking Update : 1347

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 17 October 2025

⏱️ 9 minutes

🧾️ Download transcript

Summary

Upgrade your biology in 10 minutes with this week’s rundown from Dave Asprey. T


This episode covers:

• Longevity Scores Are Going Mainstream

Elegant Hoopoe’s new clinics are using 56 biomarkers to track biological aging — and early users are reporting up to six years reversed in under two months. Could scoring systems replace reactive healthcare?

Source: Morningstar via PR Newswire — https://www.morningstar.com/news/pr-newswire/20251014ln95054


• AI Heart Scans Spot Trouble Sooner

Hospitals are using machine learning to analyze echocardiograms in real time — making heart diagnostics faster, cheaper, and more accurate, even without top specialists on site.

Source: Crescendo.AI News — https://www.crescendo.ai/news/latest-ai-news-and-updates


• Brain Training That Rebuilds Neurotransmitters

McGill’s INHANCE trial shows that 10 weeks of digital training on BrainHQ doesn’t just improve memory — it chemically rejuvenates acetylcholine pathways. That’s measurable neuroplasticity.

Source: Longevity.Technology — https://longevity.technology/news/brain-training-restores-youth-to-aging-minds/


• HLTH 2025 Unveils Digital Twins & Real-Time Immune Wearables

This year’s HLTH conference put bio-individuality front and center: AI twins that simulate your biology, hormone-tracking wearables, and apps syncing with EMRs to turn raw data into real decisions.

Source: HLTH Official — https://hlth.com/2025event


• One Blood Test, Many Diagnoses

New multi-panel tests rolling out in clinics screen for dozens of diseases from a single draw — boosting compliance, streamlining early detection, and making full-spectrum testing routine.

Source: Instagram Science Updates — https://www.instagram.com/p/DP0oGGTiiT5/


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality. 


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. 


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. 


Keywords: longevity score, elegant hoopoe, AI heart scans, brainHQ, acetylcholine, McGill INHANCE trial, HLTH 2025, digital twins, hormone wearables, immune tracking, biological age, multi-panel blood test, early detection, personalized medicine, Dave Asprey, Human Upgrade, biohacking news, health tech, performance medicine, smart diagnostics


Thank you to our sponsors!  

-SKILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off.

-EMR-Tek | https://www.emr-tek.com/DAVE and use code DAVE for 40% off.


Resources:  

• Danger Coffee: https://dangercoffee.com/discount/dave15 

• Dave Asprey’s BEYOND Conference: https://beyondconference.com 

• Dave Asprey’s New Book – Heavily Meditatedhttps://daveasprey.com/heavily-meditated 

• Upgrade Collective: https://www.ourupgradecollective.com 

• Upgrade Labs: https://upgradelabs.com 

• 40 Years of Zen: https://40yearsofzen.com 


Timestamps: 

0:00 — Introduction

0:18 — Story 1: Elegant Hoopoe Longevity Score

1:26 — Story 2: AI-Assisted Echocardiograms

2:17 — Story 3: Brain HQ Cognitive Training Study

3:03 — Story 4: Digital Twins at HLTH Conference

4:13 — Story 5: Single Vial Blood Testing

5:04 — Five Day Experiment

5:46 — Closing

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Transcript

Click on a timestamp to play from that location

0:00.0

I'm Dave Asprey. That's Dave spelled D-A-I-V-E.

0:05.0

And this is your 10-minute weekly upgrade on the biggest stories in biohacking, longevity, and the world of health. Let's go.

0:15.0

If your light environment isn't dialed in, your biology isn't either. And if you're not using light as a performance tool, you're leaving results on the table,

0:24.8

every single day.

0:26.2

The right light wavelengths unlock recovery, energy, and clarity in ways most people never

0:31.5

tap into.

0:32.7

EMR Tech's Krypton UV line puts that power in your hands with red, near-infrared, UVA, and UVB all in one system.

0:40.3

They have something for everyone.

0:42.3

From the compact Krypton Micro and Mini to the modular 606 watt and 1612 watt, each device lets you choose

0:50.3

your wavelengths, your timers, and how deep you want to go with your setup.

0:55.1

I personally use the Ultron. It's a beast. Full body coverage, built-in timers, and high

1:00.7

output light from premium components. Whether you're sinking your circadian rhythm or designing

1:06.3

a pro-level light environment, EMR tech lets you scale it your way with precise control.

1:12.8

Go to EMR-t-T-E-K.com slash Dave and use code Dave for 40% off.

1:20.4

How many nights have you stared at the ceiling, counting the hours until morning?

1:25.4

Maybe you try to sleep supplement, but it knocked you out and left

1:29.0

you groggy, like you traded one problem for another. Poor sleep doesn't just make you tired.

1:34.3

It kills your performance, slows your brain down, and speeds up aging. Kill Switch from

1:39.6

Switch supplements solves that problem. It works with your biology instead of against it. It contains

1:45.6

five gut-friendly, extensively researched ingredients like gaba, magnesium glycinate, and tart cherry extract

1:52.8

to help you fall asleep naturally, stay asleep, and wake up clear. And it's in the form of a

1:57.9

delicious, sugar-free, no-b-s-hot-coco drink.

...

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