#052 New Omega-3, sulforaphane research, and more! [Kevin Rose Show]
FoundMyFitness
Rhonda Patrick, Ph.D.
4.8 • 5.5K Ratings
🗓️ 6 January 2020
⏱️ 97 minutes
🧾️ Download transcript
Summary
This episode was originally recorded for The Kevin Rose Show. Given some of the unique discussions we had, I had no choice but to ask the great Kevin Rose if he would let me re-post it over here on the FoundMyFitness podcast feed. A request which he graciously obliged.
In this episode, you'll discover:
- 00:00:00 - Introduction
- 00:08:00 - Increasing omega-3 levels in the brain with phospholipid DHA
- 00:27:23 - Metformin's effects on longevity and possible harms
- 00:48:23 - Fasting and NAD+ supplementation
- 00:50:05 - Getting sulforaphane from food and supplements
- 01:06:57 - Magnesium L-threonate efficacy for brain health
- 01:13:44 - Sauna use mimics exercise, improving heart and brain health
- 01:23:48 - New FMF Membership
If you’re interested in learning more, you can read the full show notes here: https://www.foundmyfitness.com/episodes/rhonda-krs-2
Join over 300,000 people and get the latest distilled information on sulforaphane research straight to your inbox weekly: https://www.foundmyfitness.com/newsletter
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Transcript
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| 0:00.0 | Hey folks, today's episode was originally recorded for the Kevin Rose show. Many of you may already be |
| 0:06.4 | familiar with Kevin thanks to his history as a notable personality in the technology world. |
| 0:11.4 | His frequent guest appearances on the Tim Ferriss show and the many, many podcasts he's |
| 0:16.8 | hosted over the years. However, those of you who are not familiar with Kevin, he comes at a lot |
| 0:22.4 | of this health and lifestyle stuff as an honest to goodness hard core and equals one self-experimenter. |
| 0:28.4 | I think this really imparts a certain spirit of practicality and implementation |
| 0:32.8 | emphasized a little more in this conversation than others I've had. Not to mention he has |
| 0:38.2 | quite a few highly relevant anecdotes he drops in too. Given some of the unique discussion we had, |
| 0:44.6 | I had no choice but to ask the great Kevin if he would let me repost it over here on the |
| 0:49.5 | Foud My Fitness Podcast feed, a request which he graciously obliged. In this discussion with Kevin, |
| 0:56.4 | we discuss the unique value phospholipid H.A. has due to its propensity to be metabolized |
| 1:02.6 | into a form of omega-3 D.H.A. metabolite that utilizes a specialized system of active transport |
| 1:09.3 | mediated by a transporter called M.F.S. D.2.A., which helps get the D.H.A. across the blood brain |
| 1:16.0 | barrier. This is important because an alternative means of transport, which is passive diffusion, |
| 1:22.5 | may become less effective as disease and aging impairs the blood brain barrier. |
| 1:27.7 | With as important as omega-3 D.H.A. is for the brain, finding new and better ways to get it |
| 1:33.2 | transported into the brain may be good news. While phospholipid H.A., which is uniquely found in |
| 1:39.0 | some specialized sources like fish row, where it makes up up to 40% of the total D.H.A. content |
| 1:45.1 | may stack the deck in favor of getting a greater quantity of this actively transported D.H.A. |
| 1:50.0 | metabolite called D.H.A. Lysophosphatylcholine, where we also end up with more of this metabolite |
| 1:56.3 | just through greater intake of marine omega-3 fatty acids as a whole. Since at least some of the D.H.A. |
| 2:02.4 | Lysophosphatylcholine gets produced even from more conventional forms of D.H.A. we get, |
... |
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