#004 Bruce Ames on Triage Theory, Longevity Vitamins & Micronutrients

FoundMyFitness

Rhonda Patrick, Ph.D.

Nutrition, Health & Fitness, Medicine

4.8 • 5.8K Ratings

🗓️ 12 February 2015

⏱️ 43 minutes

🔗️ Recording | iTunes | RSS

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Summary

Dr. Bruce Ames

In this podcast, Dr. Rhonda Patrick interviews her mentor, Dr. Bruce Ames, about his triage theory and other nutrition topics. Dr. Ames was the 23rd most-cited scientist between 1973 and 1984, which is evidence of his long and productive career investigating human health and disease. Dr. Ames continues his research expanding our knowledge of nutrients such as vitamin D and its role in Autism spectrum disorder.

In this episode, we discuss...

(00:00) Introduction
(04:18) Dr. Ames discovers vitamin deficiency-induced DNA damage
(10:35) Triage theory explains nutrient rationing
(14:37) Nutrient deficiencies cause insidious damage and accelerate aging
(25:25) Expanding the list of essential vitamins (e.g., lutein & zeaxanthin)
(31:05) A Western diet pattern is mostly empty calories
(36:46) Challenges running randomized double-blind clinical trials in nutrition
(38:12) Nutrition is not the focus of our current healthcare system
(42:15) Dr. Ames' philosophy about healthy and delicious foods

If you're interested in learning more, you can read the full show notes here.

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Transcript

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0:00.0	Dr. Ronda Patrick here. Today I'm sitting here with my friend and my mentor Dr.
0:04.5	Bruce Ames. Bruce has had an enormous influence over my research and as you
0:08.4	hear him speak today that'll become quite evident. Bruce has had an
0:11.6	amazingly prolific scientific career he's published over 550 papers naming
0:17.1	him the title as a 23rd most top scientist page. 23rd most top-sciented
0:22.7	scientist across all different fields from 1973 to 1984. Bruce most
0:29.3	recently Bruce and I have co-authored two papers together one that was published
0:33.3	last February on the role vitamin D plays in serotonin production and how this
0:37.5	relates to autism. And the second paper which was just recently accepted for
0:41.7	publication is on vitamin D and the merino mega-3 fatty acids EPA and DHA and
0:46.7	what role they play in ADHD by polar disorders schizophrenia and impulses
0:50.8	behavior. Bruce is a professor at Maritus at University of
0:54.0	California in Berkeley and he is now the director of the nutrition and
0:58.4	metabolism center at Children's Hospital Oaken Research Institute where I have
1:02.4	the pleasure of working with him every day. Bruce is the inventor of the Ames
1:07.4	mutagenicity test which for those who don't know what that is it's a very
1:11.9	simple and cheap test that uses bacteria to test whether or not chemical
1:15.4	compounds can be immunogen which means that they contain things that can damage
1:21.4	DNA and cause a mutation and thus can be a carcinogen which can cause cancer.
1:26.2	It's Bruce's Ames test that identified that one of the main components in
1:31.4	permanent hair dyes back in the 1970s contained a chemical in it that was
1:36.9	mutagenic and thus a potential carcinogen and he published a paper on that
	...

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