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Dr. Joseph Mercola - Take Control of Your Health

Your Skin's Secret Weapon: The Power of Your Microbiome - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Briana Mercola

Health & Fitness, Health, Alternative Health

4.61.5K Ratings

🗓️ 10 June 2025

⏱️ 8 minutes

🧾️ Download transcript

Summary

Story at-a-glance

  • Your skin microbiome helps protect against UV radiation damage by metabolizing harmful cis-urocanic acid (cis-UCA) using an enzyme called urocanase, preventing immunosuppression and inflammation after sun exposure
  • Urocanase-positive bacteria rapidly respond to UVB exposure, shifting skin microbiome composition within hours and creating a protective feedback loop that supports overall skin health
  • Conventional sunscreens often disrupt beneficial skin bacteria, while certain microbes produce protective compounds like pigments, antioxidants, and enzymes that naturally neutralize harmful UV radiation
  • Linoleic acid (LA) from vegetable oils accumulates in skin cells, making them vulnerable to UV damage. Conversely, C15:0 fat can eventually replace LA in cell membranes
  • Reducing LA intake and supplementing with 2 grams of C15:0 daily can help boost skin health in 12 to 18 months, enabling greater sun resilience without relying on conventional sunscreens

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to Dr. Mercola's cellular wisdom.

0:04.0

Stay informed with quick, easy-to-listen summaries of our latest articles, perfect for when you're on the go.

0:09.0

No reading required. Subscribe for free at Mercola.com for the latest health insights.

0:15.0

When you step into the sun tomorrow, what if the microscopic community living on your skin already knows how to protect you,

0:22.3

better than sunscreen, and faster than any lotion? Hello, and welcome to Dr. Mercola's cellular

0:28.2

wisdom. I'm Ethan Foster, and today we're revealing how your skin microbiome forms a living

0:33.8

shield against ultraviolet damage. I'm Alara Sky. In the next few minutes, you'll hear how

0:39.2

specific bacteria deploy an enzyme called Euroconase to dismantle a harmful compound that appears on

0:45.3

your skin after UVB exposure. We'll stay grounded in Dr. Murkola's article, outlining exactly how

0:51.9

these microbes work and what actions help them thrive.

0:55.0

Let's start with the problem. UVB rays convert trans-eurocanic acid, normally harmless,

1:02.0

into cis-eurocanic acid, or cis-UCA. CISUCA suppresses your local immune response,

1:09.0

sparks inflammation, and sets the stage for DNA damage.

1:13.6

The Journal of Investigative Dermatology study asked whether bacteria equipped with Eurocanase could neutralize CISUCA before it harms you.

1:22.6

The answer was a decisive yes. Within hours of UVB exposure, populations of Eurocanas positive bacteria,

1:30.6

especially Staphylococcus epidermitis, rose sharply. By metabolizing cis-UCA into harmless

1:37.0

byproducts, they stopped the immunosuppression cascade, reduced redness, and protected DNA integrity.

1:46.8

The speed here is striking. Measurable benefits appeared the same afternoon. Researchers confirmed the effect by disinfecting skin patches to remove

1:52.3

those microbes. Where bacteria were stripped away, cis-UCA's damage hit full force, more inflammation,

1:59.8

more swelling, more immune disruption. That side-by-side

2:03.3

comparison shows why preserving your native skin community matters more than slathering on a

2:08.3

product that wipes it out. The protective story goes deeper. As Eurocene's positive strains feast

...

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