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BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause

Your Peptide Guide: BPC-157, GHK-Copper, GLP-1s & Body Composition with Kyal Van Der Leest

BETTER! with Dr. Stephanie Estima | Strength, Body Composition & Perimenopause

Dr. Stephanie Estima

Intimacy, Menopause, Betterpodcast, Nutrition, Women's Health, Menstruation, Hormones, Optimization, Sex, Fitness, Sleep, Dr. Stephanie, Health & Fitness, Science, Parenting, Motherhood, Health, Self Care, Drstephanie, Mindset, Alternative Health, Self Love

4.8 β€’ 613 Ratings

πŸ—“οΈ 9 March 2026

⏱️ 77 minutes

🧾️ Download transcript

Summary

Nutritionist, naturopath, and peptide formulator Kyal Van Der Leest breaks down the peptides that actually matter for midlife women β€” from BPC-157 (the Swiss Army knife of peptides) to GHK-Copper for skin-from-within glow-ups, to the real talk on GLP-1s that nobody's having. Watch the full episode at https://youtu.be/XFte5B2VzWI

Transcript

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0:00.0

I'll make it really, really simple. Oral peptides for the most part don't work.

0:07.0

I say that, owning level up that sell oral peptides.

0:12.0

80% of your immune system is harbored around your gut lining. So if you're doing things like alcohol,

0:18.0

antibiotic use, pesticides, glyphosate, all those things

0:21.5

are coming in via your diet, they're directly opening up the barriers of your gut and causing

0:26.9

inflammation of the gut lining. I would go so far as to say every autoimmune disease if you

0:32.4

are healing the gut will have some level of resolution. And the consequences of taking the GLP ones are that slowed motility very commonly

0:41.4

leads to bacterial overgrowth in the gut.

0:44.0

Because the food is taking so much longer to pass through, it's at a very annoying

0:48.3

side effect of, yes, I've lost weight, but now I'm bloated and I can't digest things

0:52.0

anymore properly.

0:53.5

BPC is just so commonly known.

0:55.5

It's on the tongue of everyone in podcasting and even media, a lot of celebrities, the Kardashians,

1:01.2

or Zach Efron or whoever it is, everyone's taking BPC.

1:09.2

Hello, my friends. Welcome to another episode of Better with Dr. Stephanie.

1:12.8

It's me, your host, Dr. Stephanie Estima.

1:15.3

And do you ever find yourself sometimes you're watching, you know, whatever you're watching

1:19.8

and a commercial comes on and it's about a Zempec or Wagovi or Dersepotide or whatever it is?

1:24.0

And you're like, hmm, interesting.

1:25.9

Did you know that that's a peptide?

1:27.4

I think that

1:28.2

many of us don't actually recognize that GLP-1s, which is the talk of the town, the darlings of

...

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