Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430
The Human Upgrade: Biohacking for Longevity & Performance
Dave Asprey
4.6 • 7.4K Ratings
🗓️ 12 March 2026
⏱️ 68 minutes
🧾️ Download transcript
Summary
Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it.
-Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR
Host Dave Asprey sits down with Dr. Justin Houman, a nationally recognized urologist and Assistant Professor of Urology at Cedars-Sinai Medical Center. Fellowship-trained and specializing in men's health, male fertility, and sexual medicine, Dr. Houman combines cutting-edge medical advancements with holistic lifestyle strategies to help men optimize testosterone, sexual health, and reproductive performance at every age.
Together, Dave and Dr. Houman tear through the myths, the bad science, and the outdated medical dogma around testosterone, erectile function, fertility, and male sexual health. They cover everything from why testosterone levels have collapsed in a single generation, to the real story behind the FDA black box warning, to practical protocols for men who want to optimize without sacrificing fertility. This is the masterclass on men's health that no one else is having on record.
This is essential listening for anyone serious about biohacking, longevity, human performance, hormone optimization, brain optimization, anti-aging, functional medicine, mitochondria, and Smarter Not Harder approaches to male health.
You'll Learn:
- Why testosterone levels in 40-year-old men are 30 percent lower than their fathers and what is driving the collapse
- How low testosterone connects to anxiety, depression, high cholesterol, blood sugar dysregulation, and all-cause mortality risk
- The truth about the original testosterone and heart attack study and why it still has not been retracted
- How to preserve fertility while on TRT using Clomid, enclomiphene, and HCG
- Why daily low-dose Cialis is one of the cheapest and most effective longevity drugs available
- What shockwave therapy, PRP, exosomes, and Botox injections actually do for erectile function
- How red light therapy at 660 and 850 nanometers supports testosterone production and nocturnal erections
- The supplement stack including ashwagandha, tongkat ali, fadogia agrestis, and creatine that supports healthy hormone levels
- Why porn-induced ED is epidemic in young men and how to reverse it
- How PT-141 and peptides fit into a complete male optimization protocol
Thank you to our sponsors!
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Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: testosterone, low testosterone, TRT, testosterone replacement therapy, male fertility, erectile dysfunction, ED, men's health, sexual health, hormone optimization, Dave Asprey, biohacking, longevity, anti-aging, human performance, Dr. Justin Houman, Cedars-Sinai, urologist, shockwave therapy, PRP, exosomes, Botox penis, red light therapy, nitric oxide, Cialis, tadalafil, Viagra, sildenafil, PT-141, Melanotan, peptides, ashwagandha, tongkat ali, fadogia agrestis, creatine, Danger Coffee, Smarter Not Harder, Kyzatrex, clomid, enclomiphene, HCG, prolactin, cabergoline, porn-induced ED, refractory period, fertility, sperm health, spermatogenesis, FSH, LH, estrogen, aromatization, functional medicine, supplements, mitochondria, circadian rhythm, sleep optimization, cortisol, microplastics, inflammation, cardiovascular health, dementia, all-cause mortality, nocturnal erections, penile health, male optimization
Resources:
• Learn More About Dr. Houman’s Work At: https://houmanmd.com/
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/dave15
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Timestamps:
00:00 – Introduction
01:15 – Low Testosterone Epidemic
04:23 – Ejaculation & Testosterone
07:30 – Refractory Period & Aging
09:58 – Porn-Induced ED
11:09 – Cabergoline & Prolactin Management
12:42 – Oral Testosterone
13:24 – Testosterone Target Levels
16:46 – Supplements for Testosterone
18:46 – Anxiety-Based ED
26:23 – Penis Enhancement Options
27:37 – Shockwave Therapy
28:57 – Cialis for Longevity
29:56 – Fat & Filler Injections
34:50 – Pre-Sex Optimization
40:13 – Red Light Therapy
42:18 – Heat & Cold for Testosterone
43:35 – Underwear & Microplastics
44:58 – Testosterone & Fertility
49:15 – HCG & Preserving Fertility
52:00 – Testosterone Dosing Timing
53:22 – Creatine & Mitochondrial Health
55:20 – Overtraining Effects
56:24 – Peptides (PT-141)
59:08 – Optimal Diet for Fertility
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Transcript
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| 0:00.0 | A 40-year-old today, his testosterone levels are about 30% lower than a 40-year-old, like their father when he was 40 years old. |
| 0:06.5 | Anxiety, depression, that could be a real warning sign for low testosterone. |
| 0:09.7 | When you have low testosterone levels, you predisposed to having higher cholesterol levels, higher blood sugar levels. |
| 0:14.2 | That's kind of a laundry list of how to make your life suck. |
| 0:16.9 | So in the 90s, the first study that came out looking at testosterone, it came out and it showed it had increased risk of heart attack. It was a horrible study. Since then, I think there's been maybe 24, 25 studies. Literally, all of them have disproven that original study. But to this day, they still won't redact that original study. Men with adequate testosterone have a much lower risk of all cause mortality. These guys from normal testosterone levels. |
| 0:37.9 | They live longer. |
| 0:38.8 | They have less risk of heart attack, less risk of stroke. |
| 0:40.8 | What makes men into men and how we can stay that way so that your biology can do all the things that it's supposed to do? |
| 0:48.6 | You're listening to The Human Upgrade with Dave Asprey. |
| 0:55.1 | If you've been listening for a while, you know that biohacking applies for men and women. |
| 1:01.1 | And that's because the basic rules are the same. |
| 1:03.1 | Have functioning mitochondria. |
| 1:04.5 | Get your circadian biology in order. |
| 1:06.5 | And set up the environment around you so that it supports you so that your biology can do all the things |
| 1:12.4 | that it's supposed to do and there are also some differences for men and women i've done lots of |
| 1:18.3 | episodes specifically on paramenopause on fertility and those are focused more on women's health |
| 1:24.8 | this episode is focused on men's health. |
| 1:28.8 | And specifically, testosterone, what happens in the bedroom, and other things that are around |
| 1:34.5 | reproduction, but we're going to take a deep dive into, well, what makes men into men and how |
| 1:41.1 | we can stay that way. And our guest today is a physician who's nationally recognized |
| 1:47.9 | in the field of urology at Cedar Sinai. And he looks at men's health, at male fertility, and |
| 1:55.0 | sexual medicine. His name is Dr. Justin Human. Justin, welcome to the human upgrade. |
... |
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