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The Human Upgrade: Biohacking for Longevity & Performance

Your Organic Protein Powder Is Slowly Killing You : 1441

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Diet, Education, Wellness, Nutrition, Self-improvement, Brain, Meditation, Health & Fitness, Fitness, Hacking, Lifestyle, Science, Fasting, Biohacking, Fat

4.67.4K Ratings

🗓️ 31 March 2026

⏱️ 68 minutes

🧾️ Download transcript

Summary

Most people buying "clean" supplements are unknowingly loading their bodies with heavy metals, rancid fish oil, and glyphosate, even inside products labeled organic and healthy. This episode breaks down exactly what the supplement industry refuses to tell you and gives you the tools to stop poisoning yourself every morning. 


-Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR 

-Grab a discount on Puori Products by visiting: https://puori.com/pages/dave?dt_id=1750934 


Host Dave Asprey sits down with Oliver Amdrup-Chamby, founder and CEO of PUORI and a serial entrepreneur in the health and wellness space with over 16 years building what has become one of the most rigorously tested supplement brands in the world. Oliver opened the first CrossFit gym in Denmark in 2006, served as Regional Director of CrossFit HQ across Europe and the Middle East, holds an Executive Program credential from Stanford, and advises longevity projects including One Thirty Labs in Copenhagen. He founded PUORI in 2009 with a single obsession: creating the cleanest third-party tested fish oil on the market. That obsession grew into a full supplement line built on batch testing every finished consumer product for environmental toxins, a standard the industry has yet to catch up to. 


Together, Dave and Oliver expose the hidden contamination crisis inside the supplement industry, from oxidized fish oil that creates inflammation instead of fighting it, to plant-based protein powders carrying up to 10 times more heavy metals than whey. They break down why organic does not mean safe, how glyphosate embeds itself directly into your collagen infrastructure and disrupts the body's ability to build healthy connective tissue, and why the omega 3 index is one of the most powerful and measurable longevity biomarkers you are probably ignoring. They also dig into the surprising brain optimization and anti-aging benefits of creatine, including new research on concussion recovery and sleep deprivation, and how foundational supplements like vitamin D, magnesium, and high-quality fish oil remain the non-negotiables that no nootropic stack can replace. 


You'll Learn: 

  • Why organic protein powder often contains more heavy metals than non-organic options 
  • How glyphosate infiltrates collagen and gets rebuilt into your body's own tissue 
  • What the omega 3 index is, why most Americans are dangerously low, and how raising it correlates with years of additional longevity 
  • Why plant-based omega 3s fail to convert to DHA and what to take instead 
  • How oxidized fish oil creates inflammation rather than reducing it, and what to look for on the label 
  • Why vitamin D deficiency persists even with regular sun exposure and how genetics affect your required dose 
  • The creatine research that has longevity doctors and neuroscientists paying attention for the first time 
  • How foundational supplements support mitochondria, metabolism, and long-term resilience in ways that trendy biohacking stacks cannot replicate 
  • What to look for in a clean supplement brand and why third-party batch testing of finished goods is the only standard that matters 

 


Thank you to our sponsors!      


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. 


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. 


Keywords: Oliver Amdrup-Chamby, PUORI supplements, fish oil oxidation, omega 3 index, heavy metals protein powder, glyphosate collagen, organic protein powder toxins, foundational supplements, creatine brain health, vitamin D deficiency, clean label testing, longevity supplements, biohacking, Dave Asprey, anti-aging, human performance, functional medicine, supplement transparency, plant-based protein heavy metals, whey protein 


Resources:   

• Grab a discount on Puori Products by visiting: https://puori.com/pages/dave?dt_id=1750934 

• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ 

• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.  

• Danger Coffee: https://dangercoffee.com/discount/dave15   

• My Daily Supplements: SuppGrade Labs (15% Off)   

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)   

• Dave Asprey’s BEYOND Conference: https://beyondconference.com   

• Dave Asprey’s New Book – Heavily Meditatedhttps://daveasprey.com/heavily-meditated  

• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ 

• Upgrade Labs: https://upgradelabs.com   

 

Timestamps: 

0:00 – Trailer 

0:47 – Introduction 

2:19 – Foundational vs. Sexy Supplements 

4:33 – Omega-3 Index Explained 

5:45 – Vegan Omega-3s & DHA 

7:39 – Fish Oil Oxidation 

8:48 – Batch Testing & Industry Transparency 

16:03 – Storing Fish Oil Properly 

17:30 – Vitamin D, Magnesium & Fish Oil Stack 

19:11 – Vitamin D Dosing & Genetics 

21:34 – RDAs & Government Nutrition Advice 

23:06 – Glyphosate in the U.S. Food Supply 

26:40 – Heavy Metals in Fish Oil 

37:44 – Protein Powders & Heavy Metals 

45:52 – Creatine for Brain & Concussion 

48:48 – TrueDark & Brain Recovery 

51:24 – Brain Scanning 

53:58 – Toxins in Plant vs. Animal Protein 

56:30 – Collagen: Sourcing & Glyphosate Risk 

1:02:26 – Outro & PUORI Discount 

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Transcript

Click on a timestamp to play from that location

0:00.0

What has changed though is that the king or the leadership has figured out that it's a lot easier to tell the peasants that their oatmeal and their brown rice protein and their vegan whatever things are superfoods and good for them.

0:13.9

And despite the evidence, they just say that because it stops revolts.

0:19.0

What we tend to see the most often is heavy metals and that's what these tests are showing. Especially in the plant-based ones. They're much worse. They're much worse. I got ten times worse than the weight base is what I was like looking at. So plants are the highest toxin so animals won't eat them. It makes a lot of sense. And then if we go straight to the plant, and that's why plant protein is cheaper. And it's not a superfood.

0:38.2

It just isn't.

0:40.3

You're listening to The Human Upgrade with Dave Asprey.

0:47.5

Want to know which foods and supplements work best for your body?

0:51.1

Viom takes the guesswork out of it.

0:52.9

Their full body intelligence test reads your RNA, not your DNA, Viom takes the guesswork out of it. Their full body intelligence test reads

0:55.7

your RNA, not your DNA, so you see what's happening in your body right now. While standard

1:02.1

labs measure around 100 markers, Viom's AI analyzes over 10,000 active pathways across your

1:09.9

gut, oral, and cellular health.

1:12.3

Then it translates that into personalized food and supplement recommendations built for

1:16.8

your unique biology. They'll tell you what foods to eat and which ones to avoid.

1:21.5

They even create custom supplements and oral care products based on your results.

1:26.3

So what you're getting is what will work for your body, not someone else's.

1:30.4

Your results update as your lifestyle changes, so your plan evolves with you.

1:35.5

Check it out at viome.com and use code 10-d-A-V-E for 10% off.

1:42.4

It's time to stop guessing and start knowing your body.

1:46.7

Today's episode is with a true health nerd. It was a background in leadership at CrossFit,

1:53.8

but more recently in longevity and 20 years in the health industry. We're going to talk about

1:59.1

foundational supplements.

2:06.1

Because there's a lot of incredibly sexy new stuff on the market, and I'm probably taking it.

...

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