4.1 • 11.9K Ratings
🗓️ 27 July 2017
⏱️ 7 minutes
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0:00.0 | This TED Talk features physiologist Jennifer Plusnik recorded live at TEDmed 2016. |
0:09.2 | Here's a question for you. |
0:12.0 | How many different scents do you think you can smell and maybe even identify with accuracy? |
0:19.6 | 100? |
0:20.9 | 300? A thousand? can identify with accuracy? 100? |
0:23.1 | 300? |
0:25.6 | 1,000? |
0:30.1 | One study estimates that humans can detect |
0:33.3 | up to one trillion different odors. |
0:35.0 | A trillion. |
0:36.8 | It's hard to imagine, |
0:40.6 | but your nose has the molecular machinery to make it happen. |
0:45.2 | Alphactory receptors, tiny scent detectors, |
0:47.3 | are packed into your nose, |
0:50.2 | each one patiently waiting to be activated by the odor or ligand that it's been assigned to detect. |
1:01.0 | It turns out we humans, like all vertebrates, have lots of olfactory receptors. In fact, more of our DNA is devoted to genes for different olfactory receptors |
1:08.0 | than for any other type of protein. Why is that? Could olfactory receptors be |
1:16.3 | doing something else in addition to allowing us to smell? In 1991, Linda Buck and Richard Axel |
1:26.0 | uncovered the molecular identity of olfactory receptors' work, |
1:30.3 | which ultimately led to a Nobel Prize. |
1:33.3 | At the time, we all assumed that these receptors were only found in the nose. |
1:39.3 | However, about a year or so later, a report emerged of an olfactory receptor expressed in a tissue other than the nose. |
... |
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