The holy grail of Alzheimer's prevention is early detection.

It's a condition that begins years, if not decades before the first symptom.

Midlife obesity, midlife type 2 diabetes, midlife hypertension are all related to increased risk for Alzheimer's disease.

Body composition matters.

And if you look at a, from a public health standpoint, we're not doing too well.

The cognitive reserve gives you more to lose before you lose it. If you're not really challenging your brain, there's not going to be that impetus for your brain to create scaffolding around your pre-existing neural networks.

Max Lugavir, you're looking pretty shredded over there. What's going on?

Thanks, brother. I've been on a bit of a cut over the past couple months, and I feel great.

I think I'm like probably around 10% body fat.

Awesome.

And just trying to be more like you.

Just trying to be like you, bro.

Thanks, man.

Yeah, no, I love the journey of like body composition, recomposition, and I've been into fitness my whole life.

I wrote my high school senior thesis on creatine monohydrate, so this is a topic that I've been, you know, obsessively interested in for a very long time, or I should say passionate about it for a very long time.

And, yeah, and, you know, my body of work began with an investigation into the many factors that keep a brain healthy over time.

But over the past couple of years, I would say, specifically, I've done a deeper dive into the knobs and levers of changing body composition with a focus on fat loss and muscle growth.

And, yeah, it's been very rewarding.

What kind of research is there around, you know, fat loss, fat accumulation, and brain health?

That's a great question.

So the 2024 Lancet Commission on dementia prevention highlighted obesity and type 2 diabetes and hypertension

as modifiable risk factors for dementia, which are obviously related to body composition.

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