4.2 • 639 Ratings
🗓️ 29 September 2014
⏱️ 2 minutes
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0:00.0 | Understanding the human body is a team effort. That's where the Yachtel group comes in. |
0:05.8 | Researchers at Yachtolt have been delving into the secrets of probiotics for 90 years. |
0:11.0 | Yacold also partners with nature portfolio to advance gut microbiome science through the global grants for gut health, an investigator-led research program. |
0:19.6 | To learn more about Yachtolt, visit yawcult.co. |
0:22.7 | .jp. That's Y-A-K-U-L-T.C-O.J-P. When it comes to a guide for your gut, count on Yacolt. |
0:34.3 | This is Scientific Americans' 60 Second Science. I'm Karen Hopkins. This will just take a minute. |
0:40.4 | Yeast. They already participate in producing some of the most popular pain-killing substances around, beer and wine. |
0:47.1 | Now, scientists have engineered yeast that can also make one of the most powerful analgesics, morphine. |
0:52.1 | Their work is in the journal Nature Chemical Biology. Opiates like |
0:55.5 | morphine and codeine are essential for treating severe pain. But making these meds isn't easy. All are |
1:00.8 | derived from opium poppies, and tens to hundreds of thousands of tons are needed to meet global |
1:05.7 | needs. The crops can also be affected by climate, disease, and even political turmoil in the countries |
1:11.2 | where the plants are grown, which further limits commercial production. To get around these |
1:15.6 | potential challenges, researchers have turned to yeast, an organism that can be grown easily |
1:20.1 | on industrial scales. The scientist inserted into yeast cells a handful of genes isolated |
1:25.4 | from the opium poppy. These genes encode the enzymes the |
1:28.7 | plants use to produce opiates. After tweaking the system to adjust the relative amounts of the enzymes, |
1:34.1 | the researchers could feed their yeast a precursor chemical called theban and get pure morphine |
1:39.4 | in return. The yeast can't yet make opiates from scratch, but with a bit more effort and a few more enzymes, yeast may produce painkillers that are prescription strength. |
1:49.0 | Thanks for the minute. For Scientific Americans' 60 Second Science, I'm Karen Hopkins. |
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