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Science Friday

Year In Space Results, Citizen Science Day, Cherry Blossoms. April 12, 2019, Part 2

Science Friday

Science Friday and WNYC Studios

Science, Life Sciences, Wnyc, Natural Sciences, Friday

4.4 • 6.3K Ratings

🗓️ 12 April 2019

⏱️ 47 minutes

🧾️ Download transcript

Summary

To find out what was happening to astronauts over longer periods of space flight, NASA put together a 10-team study of twin astronauts Scott and Mark Kelly. Scott spent a year on International Space Station, while his brother Mark lived a relatively normal life on Earth—though both regularly sent the researchers samples of their blood, urine, cognitive test results, and other data to assess their physiology over time. Scott Kelly returned to Earth in 2016, and researchers have been studying and comparing the twins ever since. The conclusion? A year in space caused a cascade of changes in Scott’s gene expression and physiology—some of which remained even after he returned to Earth. Dr. Susan Bailey, a radiation biologist at Colorado State University, explains one surprising mystery: The average length of Scott’s telomeres, a part of DNA that usually shortens with aging or other kinds of stress, increased. And Dr. Christopher Mason at Weill Cornell Medicine explains how spaceflight ramped up genes associated with Scott Kelly’s immune system and what remained different even months after his return to Earth. Patients with Alzheimer’s disease can experience decreased blood flow in their brains caused by white blood cells sticking to blood vessels that can cause a block. Researchers at Cornell University have found that these stalls happen in the tiniest blood vessels, the capillaries. Understanding these capillary blocks could help find new Alzheimer’s treatments—and to do that, the researchers have to look through hundreds of thousands of images of blocked capillaries. Now, you can help. Physicist Chris Shaffer, who is on the Cornell University team, teamed up with Pietro Michelucci to develop a citizen science game called Stall Catchers that uses the power of the crowd to help identify these stalls. They talk about how Stall Catchers can help with their data—and the one-day megathon when you can participate. By 1918, the British naturalist and ornithologist Collingwood Ingram had tired of studying birds, but soon became obsessed with two magnificent flowering cherry trees planted on his property. He went to Japan and hunted for wild cherries all over the country on foot, horseback, and even from the sea, using binoculars to spot prime specimens. Throughout his travels, he became convinced that Japan was in danger of losing its multitude of cherry varieties, through modernization, development, and neglect, and he went on to evangelize for the wondrous diversity of flowering cherries in Japan, and back home in the western world. In The Sakura Obsession, Japanese journalist Naoko Abe tells Ingram's story, and the cultural history of cherry blossoms in Japan.

Transcript

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0:00.0

This is Science Friday. I'm Ira Flato. A bit later in the hour, we'll talk about the cherry blossom hunter, English ornithologist and naturalist Collingwood Ingram, who gave up studying birds to devote his life to cataloging and preserving rare flowering cherry varieties, subject of the new book, the Sakara Obsession.

0:23.3

But first, how many of you are twins?

0:24.8

That many.

0:27.6

Well, are you tired of being compared to your sibling?

0:33.4

Maybe your parents dressed you alike, or people keep asking you who was born first, right?

0:36.8

But twins, you know, have been a boon to science.

0:40.8

So many twins studies, examining the differences in their life stories, their ills, their diseases, the ultimate comparison. And now two

0:46.3

famous twins, astronauts, have lent their lives to science, specifically what happens to your

0:51.8

body after extended periods in the weightless, higher radiation levels of space?

0:57.8

We've been asking this question since the beginning of human spaceflight, and there's still a lot we don't know.

1:05.3

Astronauts have to exercise frequently to fight bone demineralization and muscle atrophy, fluid shifting their bodies in

1:13.5

microgravity, and some even have vision changes. But in 2015, NASA undertook a more ambitious

1:20.4

project to study the physiological and genetic changes of an identical twin pair.

1:26.7

And those twins were astronauts Mark and Scott Kelly.

1:30.5

Mark stayed on Earth.

1:32.2

Scott spent nearly a full year on the International Space Station.

1:36.9

And that time, they sent research teams samples of their blood, their urine.

1:40.7

They took cognitive tests and put as much of their physiology under the microscope

1:46.2

as possible to suss out what was going on in the space-born Scott cells that didn't happen

1:53.3

to his brother.

1:54.3

There's stuff that you don't see that, you know, the researchers at some point will publish papers on, you know, for instance,

2:04.8

how, you know, my DNA looked one way before flight and how he's compared before flight,

...

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