4.9 • 806 Ratings
🗓️ 26 December 2020
⏱️ 9 minutes
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0:00.0 | So, guys, Derek, moreplacemerdes.com. Today we're going to be talking about finasteride |
0:03.8 | and if it's going to inhibit you from losing fat and getting shredded or gaining muscle. So I've |
0:09.7 | talked about the gaining muscle part many times in terms of if you're inhibiting dhc production, |
0:16.3 | you actually have a subsequent rise in total testosterone levels and that amount is going to be dependent |
0:21.9 | on how much you're inhibiting 5 alpha reductase. So if you have, you know, 70% inhibition with |
0:27.2 | fanasteride, you're going to get maybe a, you know, 60 to 70% decrease in systemic DHC with a |
0:33.2 | subsequent 15% increase in testosterone and estrogen as a result of when you're inhibiting the enzyme, |
0:39.8 | now the testosterone can't convert into DHD. So now you have more testosterone and as a |
0:46.0 | consequence, more estrogen too. When you use Dutastrian, you inhibit upwards of 99% of 5 alpha |
0:52.0 | reductase activity. You have almost no Dg in your body at all, literally less than a |
0:56.6 | prepubescent girl essentially, you have a situation where 5A.R is so inhibited, even more is left |
1:03.1 | as testosterone, and consequently aromatized into estrogen, you have a 22% approximately, |
1:08.9 | give or take, increase in testosterone and estrogen. Now it doesn't necessarily mean you get a bump% approximately give or take increase in testosterone and estrogen. |
1:11.3 | Now it doesn't necessarily mean you get a bump, a giant bump in free testosterone to the point |
1:16.9 | where it's, you know, going to make a massive difference in terms of muscle growth. |
1:20.6 | However, what we do see in the clinical literature is there is no deleterious impact to muscle growth outcomes. |
1:28.8 | Like you're not going to lose a bunch of muscle because of finasteroid Dutacharya. |
1:33.2 | Now maybe downstream you could argue that actual like motor neuron recruitment in the gym is |
1:39.2 | inhibited because of lack of DHD, you no longer have that mind muscle connection. |
1:43.2 | You're not as snappy with the weights and as a result of using smaller loads because |
1:48.8 | you can't literally push as much weight potentially, then as a consequence you might maybe |
1:54.2 | lose some muscle, but does that actually happen in practical application? |
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