So, guys, Derek Moore, pleadsmoredates.com.

Today we're going to be talking about does finasteride, make you lose muscles.

So these are my updated thoughts on the topic.

And I have produced videos in the past that outline how there is no difference in lean muscle

accrual on testosterone versus when you're inhibiting DHD and 5 alpha reduction with

fanasteride, dutastride.

And my thoughts are slightly different now but they haven't changed

significantly but just let me elaborate on that so on paper they've done studies on this they've

inhibited dh t levels like crushed them with dastoride and found no difference in terms of muscle

accrual relative to the dhc levels and in fact, in some stances, you could argue that inhibiting

dhc can actually make you gain more muscle because if you increase your testosterone consequently

from inhibiting 5A.R, which is going to happen, you're also going to increase estrogen. Both these things

are going to contribute to animalism downstream and potentially make you build more muscle. There is a caveat

to this though whereby if you increase your SHBG or you had a high SHBG to begin with, by decreasing

DHC significantly, you have to consider this. DHC has a five times higher binding affinity

for SHBG than testosterone and testosterone has a higher affinity than estrogen.

So by lowering your DHC significantly, you now have a significant more amount of SHBG that can bind up that testosterone, which can essentially, you know, render it not necessarily inactive, but it's not, you know, freely

available to tissues to transcribe anabolic effects.

And there's obviously caveats to this too, or delivery via SHBG.

There's thoughts that if you have to love SHBG, that's, you know, also going to be a bad

thing.

You're going to hyper excrete testosterone.

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