In today's session, let's take a deeper dive into iron metabolism, iron overload and therapeutic

phlebotomy for individuals who have high ferritin and also hemoglobin. This is really important

for men of all ages and post-menopausal women. This is something that I see so commonly,

unfortunately, on labs that is a reflection of subacute or subclinical elevated or iron overload

and a lot of people don't know what to do about it, but the treatment and the modality

is quite simple. It's bloodletting. It's going to your local blood bank, donating blood once

or twice a year to bring down that stored iron because it turns out that iron is a catalyst.

Iron, especially elevated levels of iron, we'll talk about the blood biomarkers, the proxies,

the things to look out for in your blood work to see if this is elevated in you or somebody

know about, but iron can catalyze and help to cause oxidation of low-density lipoproteins within

the atherosclerotic plaque. It's sufficient to say that iron overload and iron excess can drive

the process of cardiovascular disease, of cardiovascular dysfunction and the coronary artery

occlusion and the narrowing of the arteries. We have a tool, my friends, that is very affordable,

that has been clinically studied, that has been shown in diabetic patients and also patients

with cardiovascular disease to reduce the prevalence of those conditions. Some of the things we'll

also talk about today is fatty liver disease and how fatty liver disease can actually be reversed

by just donating blood. There's a paper actually. We're going to talk about it. I'll just give you

a little hint at what it's called here. Iron depletion by phlebotomy improves insulin resistance

in patients with non-alcoholic fatty liver disease. We know fatty liver disease, unfortunately,

is so common. It's not just for meeting dietary fat. We know that insulin and hyperinsulinemia

causes changes in iron metabolism, iron absorption, and all aspects of iron physiology and ferrets

in metabolism. This paper found that in individuals who have a histologically defined non-alcoholic

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