Why Thyroid Treatment Isn’t Working | McCall McPherson PA-C

As a Woman

Natalie Crawford

Medicine, Health & Fitness

4.8 • 1.1K Ratings

🗓️ 31 March 2026

⏱️ 48 minutes

🔗️ Recording | iTunes | RSS

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Summary

The medical system often reduces your thyroid—the engine of your metabolism, mood, and fertility—to a single number: TSH. In this episode, Dr. Natalie Crawford sits down with thyroid expert and Modern Thyroid Clinic founder McCall McPherson to discuss why "normal" lab ranges are leaving millions of women debilitated. McCall shares her own harrowing journey of being gaslit by the medical community while struggling to function, and together, they provide a roadmap for how you can take agency over your hormones and demand better care. What You’ll Learn: The critical distinction between "crude oil" and "gasoline" hormones and why TSH testing alone fails to identify hypothyroidism in many symptomatic women. The surprising 10-year gap between the onset of thyroid symptoms and a formal diagnosis, and how frequent full thyroid panels can change your health trajectory. How subclinical hypothyroidism and Hashimoto’s disease directly impact unexplained infertility and double the risk of miscarriage during the fertility journey. The specific role of low dose Naltrexone (LDN), selenium, and gut health in reducing thyroid antibodies and achieving long-term autoimmune remission. Why conventional levothyroxine and Synthroid treatments often leave patients "stockpiling" hormones they can't use, and the importance of thyroid optimization over simple replacement. Find McCall McPherson McCall McPherson, PA | Modern Thyroid Clinic Instagram: @mccallmcphersonpa Resources: Pre-Order The Fertility Formula ⁠https://www.nataliecrawfordmd.com/book⁠ Newsletter: nataliecrawfordmd.com/newsletter Instagram: @nataliecrawfordmd Youtube Channel: Natalie Crawford MD Interested in becoming a patient?: Fora Fertility Earn FREE CE/CME: Learn at Pinnacle App This episode is brought to you by The Pinnacle Podcast Network. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	If we can get warning signs, intervene earlier, this is absolutely what we want to do.
0:05.0	Medicine is really only checking one hormone, your T-SH, your brain's hormone, and we need to look deeper.
0:11.0	You're talking about changing the trajectory of your entire health journey here.
0:14.0	You can absolutely be debilitated in, quote, normal lab ranges for thyroid.
0:19.0	If you can't treat what you don't know.
0:24.8	These women deserve better when they're on their fertility journey.
0:29.0	People don't need to be on excessive amounts of thyroid hormone to feel well.
0:31.9	Why wait for it to fail completely before we pay attention to it?
0:37.4	Welcome back to the As a Woman podcast. I'm your host, Dr. Natalie Crawford, and today we're talking
0:40.2	all about the thyroid. If you've ever struggled with fatigue, brain fog, weight changes,
0:45.2	irregular cycles, infertility, anxiety, or just feeling off, and your thyroid labs were brushed
0:50.9	aside and told everything was fine, this episode might be for you,
0:54.5	because thyroid health influences everything, your metabolism, your ovulation, pregnancy
0:59.1	outcomes, mood, and long-term hormone function. Yet, it's often reduced to just a single number.
1:04.5	So today I'm joined by McClell McPherson, thyroid expert, PA, and founder of modern thyroid
1:10.2	clinic. We're diving into what
1:12.4	thyroid optimization really means, where conventional testing can fall short, how your thyroid
1:17.7	hormones impact your life, and really how to advocate for yourself and your own care.
1:22.0	Nicole, thank you so much for being here.
1:23.8	Thank you so much for having me. I'm so glad we finally made this happen.
1:27.3	I know. We've been
1:27.9	trying for such a long time. And I just have to say from the start, like, I adore you. I adore your
	...

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