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Dr. Joseph Mercola - Take Control of Your Health

Why Skipping Beef Liver Could Hurt Your Pancreas - AI Podcast

Dr. Joseph Mercola - Take Control of Your Health

Briana Mercola

Health & Fitness, Health, Alternative Health

4.61.5K Ratings

🗓️ 31 July 2025

⏱️ 8 minutes

🧾️ Download transcript

Summary

Story at-a-glance

  • Research shows vitamin B12 rapidly replenishes adenosine triphosphate (ATP) levels in pancreatic cells, preventing destructive enzyme activation that causes acute pancreatitis inflammation
  • People with naturally higher vitamin B12 levels show significantly lower risk of developing acute pancreatitis, independent of lifestyle factors
  • Vitamin B12 enhances energy metabolism by converting methylmalonyl-CoA to succinyl-CoA, stabilizing cell membranes and containing digestive enzymes properly
  • Early vitamin B12 administration provides greatest protection, with 1,000-2,000 micrograms daily recommended for supplementation or monthly injections for severe deficiency
  • Combine vitamin B12-rich foods like grass fed liver alongside minimal vegetable oil intake and regular exercise to support overall pancreatic health

Transcript

Click on a timestamp to play from that location

0:00.0

Could a single nutrient you probably overlook every morning be the key to shielding your

0:04.5

pancreas from the sudden, searing pain of acute pancreatitis?

0:09.5

Welcome to Dr. Mercola's cellular wisdom. Stay informed with quick, easy-to-listen

0:14.9

summaries of our latest articles, perfect for when you're on the go. No reading required.

0:19.4

Subscribe for free at Mercola.com for the latest health insights.

0:23.7

Hello and welcome to Dr. Mercola's cellular wisdom. I'm Ethan Foster. And today we're

0:29.0

spotlighting vitamin B12 and new evidence showing how quickly it rescues energy-starved

0:34.3

pancreatic cells and stops destructive enzymes before they ignite an inflammatory

0:39.0

storm.

0:40.3

I'm Alara Sky, and it's great to be here.

0:43.6

Acute pancreatitis begins when the digestive enzymes your pancreas normally stores in an

0:48.8

inactive form switch on too early.

0:51.7

Instead of working in the small intestine, they start breaking down your own tissue,

0:56.0

sparking intense pain, and raising your risk of infection, kidney failure, and diabetes.

1:03.0

Researchers now see vitamin B-12 as a direct break on that runaway process.

1:09.0

A genetic analysis of more than half a million people found that individuals born with

1:14.1

naturally higher blood, vitamin B, 12 levels, have a markedly lower risk of ever developing

1:20.2

acute pancreatitis. Even after lifestyle and diet are factored out. The association is so strong

1:27.1

that scientists suspect B-12 status

1:29.3

may be one of the few modifiable levers you can control. Laboratory work in mice supports

1:35.0

that conclusion. Investigators disabled the transcobalamin receptor, the doorway through which

1:41.1

cells absorb vitamin B-12, and then triggered pancreatitis.

...

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