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Nature Podcast

Why low temperatures could help starve tumours of fuel

Nature Podcast

podcast@nature.com

Science, Technology, News

4.5893 Ratings

🗓️ 10 August 2022

⏱️ 23 minutes

🧾️ Download transcript

Summary

Cold exposure in mice activates brown fat to deny tumours glucose, and the future of extreme heatwaves.


00:45 How cold temperatures could starve tumours

A team of researchers have found that exposing mice to the cold could starve tumour cells of the blood glucose they need to thrive. They showed that the cold temperatures deprived the tumours of fuel by activating brown fat – a tissue that burns through glucose to keep body temperature up. The team also showed preliminary evidence of the effect occurring in one person with cancer, but say that more research is needed before this method can be considered for clinical use.


Research article: Seki et al.


08:59 Research Highlights

Evidence of the world’s southernmost human outpost from before the Industrial Revolution, and how jumping up and down lets canoes surf their own waves.


Research Highlight: Bones and weapons show just how far south pre-industrial humans got


Research Highlight: How jumping up and down in a canoe propels it forwards


11:24 The future of extreme heatwaves

Climate scientists have long warned that extreme heat and extreme heatwaves will become more frequent as a result of climate change. But across the world these events are happening faster, and more furiously, than expected, and researchers are scrambling to dissect recent heatwaves to better understand what the world might have in store.


News Feature: Extreme heatwaves: surprising lessons from the record warmth


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Transcript

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0:00.0

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0:03.7

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0:19.4

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0:22.2

As voted by the mobile industry awards 2024,

0:24.7

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0:26.7

24 month plan. Unlimited UK only.

0:29.0

X 20% fat.

0:34.1

In a experiment,

0:37.2

we don't know yet. Why is it like so far?

0:40.4

Like it sounds so simple.

0:41.7

They had no idea.

0:43.1

But now the data's...

0:44.3

I find this not only refreshing, but at some level astounding.

0:52.1

Nature.

0:54.0

Nature. Welcome back to the nature podcast.

0:58.4

This week, how cooling brown fat could starve tumors of glucose and learning lessons from record-breaking heat waves.

1:07.6

I'm Benjamin Thompson.

1:18.4

Okay. waves. I'm Benjamin Thompson. Cancer cells are notorious for their ability to divide and divide and divide and divide and

1:27.2

well, you get the picture.

1:29.6

But this ability requires something important.

...

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