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a16z crypto show

When Bots Have Bank Accounts: The Rise of the Agent Economy (With Sean Neville, Catena Labs)

a16z crypto show

Andreessen Horowitz

Distributed Computing, Blockchain, Art, Innovation, Web 3, Technology, Culture, Internet, Public Goods, Business, Decentralization, Open Source, Creator Economy, Music, Gaming, Cypherpunk, Visual Arts, Crypto, Arts, Web 3.0, Entertainment, Computing, Computer Science, Blockchains, Entrepreneurship, Ownership, Web3, Cryptography

4.466 Ratings

🗓️ 3 March 2026

⏱️ 21 minutes

🧾️ Download transcript

Summary

When AI agents start earning, spending, lending, and investing, the internet’s money layer needs to evolve fast. Sean Neville—cofounder of Circle, architect of USDC, and now cofounder of Catena Labs—lays out his thesis for an agent-native economy built on programmable dollars and “AI-native banks.”

Transcript

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0:00.0

You co-founded Circle and now you're working on something new, an AI bank.

0:04.0

The internet itself is going agent native. Really agents doing anything. We think they'll need to get paid. They'll need to make payments. They'll need to generate some sort of return or be rewarded for holding a balance. They may want to lend. They may want to apply for credit in certain situations. They'll want to do all the things that a bank might do for a business. ultimately we'll need an AI bank that is actually for other AIs.

0:22.0

You believe that these agents are going'll need an AI bank that is actually

0:21.3

for other AIs.

0:22.3

You believe that these agents are going to be the only ones that we actually trust with our

0:25.7

assets.

0:26.7

What is going to make people won over by bots?

0:29.9

Why would you ever trust it with your money?

0:31.4

Worst outcome is you build a lot of amazing stuff that nobody wants.

0:38.5

Sean, thank you so much for being here.

0:40.1

It's a pleasure.

0:41.0

You co-founded Circle, you architected USDC, stablecoin that lots and lots of people throughout

0:46.2

crypto and beyond are now using as crypto and trad-fi sort of intersect.

0:51.1

And now you're working on something new.

0:53.3

You're building what you've described as an

0:54.6

AI bank. What do you mean by that? Well, we're taking the next step. Once we have stable coins

1:00.3

and we have the ability to represent dollars on Internet rails, what kind of new opportunities

1:05.2

that unlock? At the same time, we were contemplating that. You could see clearly the web,

1:09.7

the Internet itself, is going agent-native.

1:12.0

And after working in AI for quite some time, developed conviction that as AI actors become

1:18.4

economic participants, they will ultimately be the primary dominant economic participants in the world

1:25.1

for all kinds of activities, payments and otherwise. I think, you know, flash forward in a few years, I think they may be the only actors that we trust with our assets and the only actors that are capable of generating meaningful return on our assets. We're certainly not there today. And so what do we need to do in order to get there to unlock a, you know, I think a level of, the likes of which the world hasn't seen yet.

...

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