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The Quanta Podcast

What Makes Life Tick? Mitochondria May Keep Time for Cells

The Quanta Podcast

Quanta Magazine

Physics, Life Sciences, Science

4.7643 Ratings

🗓️ 7 February 2024

⏱️ 24 minutes

🧾️ Download transcript

Summary

Every species develops at its own unique tempo, leaving scientists to wonder what governs their timing. A suite of new findings suggests that cells use basic metabolic processes as clocks. Read more at QuantaMagazine.org. Music is “Pulse” by Geographer.

Transcript

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0:00.0

Welcome to Quantum Magazine's podcast. Each episode, we bring you stories about developments in science and mathematics.

0:13.6

I'm Susan Vallett. Just as people in different places seem to operate at different rhythms, so do different species. But that presents

0:22.7

a mystery. What governs their varied timing? A new flurry of research suggests that cells use

0:29.5

metabolic processes as clocks. That's next. You've learned from Quanta. Now we want to learn from you.

0:43.4

Quanta is conducting a series of surveys to better serve our audience.

0:47.5

Take our podcast listener survey and you'll be entered to win a free Quanta book,

0:51.7

t-shirt, or tote bag.

0:53.3

Head to quantam mag.ttypeform.com forward slash

0:58.4

podcast to answer our questions, or just click on the link in the podcast description.

1:08.0

Different species age at their own rates. Some, like the fruit fly, race to adulthood so they can

1:15.9

reproduce before their food source disappears. Humans mature slowly over decades, in part because

1:22.6

building a large, complex brain requires it. At the very beginning of an embryo's life, small tweaks in the

1:29.9

timing of when and how different tissues develop can dramatically alter an organism's form,

1:36.4

a mechanism that evolution exploits in creating new species. But what sets the tempo of an organism's

1:43.7

growth has remained a mystery. Margueretta Diaz Quadros

1:47.6

leads research focused on developmental tempo and Massachusetts General Hospital in Boston.

1:53.6

Understanding developmental timing is a really fundamental question that to me is one of the

1:59.1

most understudied areas in developmental biology. And our

2:03.7

knowledge of what controls developmental timing has really lagged behind other areas in developmental

2:10.0

biology. So we are coming in and we have an opportunity because it is so understudy to make

2:17.3

some really fundamental discoveries and descriptions, which I'm really excited about.

2:22.7

And I also think there are many labs now starting to work on this.

...

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