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On The Mend

What Actually Breaks Addiction: Neuroscientist Tj Power Explains

On The Mend

High Performance

Trauma, Vulnerability, Hope, Healing, Health & Fitness, Education, Menshealth, Sobriety, Personal Journals, Redemption, Society & Culture, Recovery, Growth, Addiction, Identity, Mental Health, Mentalhealth, Resilience, Self-improvement, Relapse, Alcoholism

4.9566 Ratings

🗓️ 19 January 2026

⏱️ 72 minutes

🧾️ Download transcript

Summary

This week’s guest is Tj Power, lead neuroscientist and founder of the DOSE Lab, who helps us understand what’s really happening in our brains when we feel overwhelmed, burnt out, glued to our phones, or stuck in patterns we can’t quite explain.


In this episode, TJ breaks down mental health in a way that feels human, not clinical. He talks about why so many of us feel constantly on edge, how modern life quietly rewires our brains, and why willpower alone is rarely enough when you’re dealing with anxiety, compulsive behaviours, or emotional overload. 


Rather than offering quick fixes, TJ focuses on understanding, learning how your brain actually works, why certain patterns repeat, and how small, realistic changes can help you steady yourself again.


This conversation is grounding and reassuring, for anyone realising that real change starts with understanding, not self-blame.


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Need Support?

Samaritans: Call 116 123 or visit samaritans.org

Narcotics Anonymous: na.org

Alcoholics Anonymous: alcoholics-anonymous.org.uk

Mental Health Mates: mentalhealthmates.co.uk

Shout: https: giveusashout.org

IAPT: england.nhs.uk/mental-health/adults/nhs-talking-therapies/


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Transcript

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0:00.0

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0:05.0

So I'm spending, on average, six hours, four minutes. A day on this thing. That's crazy. What exactly is dopamine?

0:16.0

Dopamine is this neurotransmitter in our brain that evolved over hundreds of thousands of years of human

0:22.9

evolution to motivate us to do hard things and take something like cleaning your home, just like a boring,

0:29.4

effortful task. Whilst you're doing it, it's not like, wow, this is so fun, it stimulates, and I'm buzzing,

0:33.8

and I'm cleaning my house. But you'll notice as the house gets cleaner, you feel a little bit of satisfaction. And then as you finish, like washing up your kitchen, you sit down the sofa to chill, this slight sense of reward appears in your brain. Do you see higher numbers with these kind of things around people with a history of addiction? Hey guys, welcome back to On the Men. This is the podcast where we look back at life's toughest moments to figure out how we move forward.

0:57.1

Now, in the past, we've released episodes about social media and effects. It often has on me.

1:02.4

I can get digitally overwhelmed at times and then have a bit of a burnout.

1:07.5

There are times when I literally get so burnt out that I stop replying. I go totally

1:13.6

distant and withdraw from life, which isn't good, right? So I think, like, of all the

1:19.6

podcasts I've done, I don't think I could have a more fitting time in my life and in the podcast

1:25.2

trajectory as today, because today we have someone I've met before

1:30.2

and I admire hugely. It is TJ Power. TJ Power, welcome to the podcast, mate. Thanks for

1:35.9

having me, my friend. I'm so pleased to see you, mate. I mean, I've got so many ways I want to go with

1:40.6

you. But I think, right, okay, I'm thinking about everyone, everyone listening and how we can get the best out of you in the time that we have, right? I mean, I've seen your stuff everywhere. I love learning for you. For those who might not know you, can you explain what you do? Yeah, so I'm a neuroscientist. I run a research lab called Dose Lab. That's so cool. I'm a neuroscientist. It's fucking dope.

2:02.8

And it studies our four primary brain chemicals are dopamine, oxytocin, serotonin and endorphins.

2:09.8

Very conveniently, the acronym happens about dose, which has basically built my whole career.

2:14.0

And we've basically turned Dose into what's called a psychological intervention, where we've

2:19.7

gamified brain chemistry into 20 core habits that help people get these chemicals back into balance.

2:25.8

We've now taken just over 85,000 people through this intervention. So we've learned a huge amount

2:31.0

about people's brain chemistry. Modern life is pretty disruptive to the natural

2:35.9

harmony these chemicals have, which creates many of the challenges we experience around burnout,

...

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