Weight Gain on HRT: What’s Really Causing It | Solo

The Dr. Tyna Show

Dr. Tyna Moore

Alternative Health, Health & Fitness

4.9 • 1.7K Ratings

🗓️ 7 February 2026

⏱️ 66 minutes

🔗️ Recording | iTunes | RSS

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Summary

EP. 247: In this episode, I share my honest experience with hormone replacement therapy and unpack why HRT is not a guaranteed weight loss solution. In fact, sometimes it can even lead to weight gain! I walk through how estrogen, progesterone, and testosterone influence appetite, insulin sensitivity, mood, and body composition, and why the wrong balance can sometimes lead to unexpected weight gain. I also explain how oral progesterone affects carb cravings, what is meant by the “Goldilocks” range for estradiol, and why how you feel means more than chasing perfect lab numbers, in my clinical opinion. Topics Discussed: → Does HRT cause weight gain? → Why am I gaining weight on progesterone? → Can hormone therapy help with menopause symptoms? → How estrogen affects metabolism in perimenopause? → Is HRT good for insulin resistance? Sponsored By: → Timeline | Support your cells and how you age with Mitopure® Gummies from Timeline. Visit https://timeline.com/DRTYNA and save up to 39% off your Mitopure® Gummies. → Cozy Earth | These viral pj’s are so good they sold out during the holidays, and now they’re back with an exclusive deal only available January 25th - February 8th. Head to https://cozyearth.com and use my code DRTYNABOGO to get these pj’s for you and someone you love! → Puori | Go to https://puori.com/DRTYNA and use the code DRTYNA at checkout to get 32% off your first Protein subscription order and get a free shaker worth $25. → Sundays | Make the switch to Sundays. Go right now to https://sundaysfordogs.com/DRTYNA30 and get 30% off your first 3 orders. Or, you can use code DRTYNA30 at checkout On This Episode We Cover: → 00:00:00 - Introduction → 00:00:29 - Dr. Tyna & hormones → 00:04:11 - Current hormone routine → 00:06:25 - Testosterone & weight gain → 00:09:32 - Middle age & weight → 00:12:21 - Goldilocks hormone levels → 00:19:36 - Estrogen vs progesterone → 00:20:22 - Combatting misinformation → 00:23:06 - Insulin antagonism → 00:27:38 - Transient insulin resistance → 00:31:53 - Oral micronized progesterone → 00:34:20 - Calories in, calories out → 00:36:02 - Estradiol → 00:39:30 - Energy storage & insulin resistance → 00:45:14 - High hormone levels → 00:48:56 - Symptoms to watch for → 00:50:27 - Detox & mitochondria → 00:51:24 - Muscle & exercise → 00:56:21 - “Work harder” & cortisol → 01:00:29 - Belly fat & testosterone Further Listening: → EP 163: Understanding The Middle Aged Middle | Solo Episode Disclaimer: Information provided in this podcast is for informational purposes only. This information is NOT intended as a substitute for the advice provided by your physician or other healthcare professional, or any information contained on or in any product. Do not use the information provided in this podcast for diagnosing or treating a health problem or disease, or prescribing medication or other treatment. Always speak with your physician or other healthcare professional before taking any medication or nutritional, herbal or other supplement, or using any treatment for a health problem. Information provided in this blog/podcast and the use of any products or services related to this podcast by you does not create a doctor-patient relationship between you and Dr. Tyna Moore. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent ANY disease.

Transcript

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0:00.0	On this episode of the Dr. Tina show, we're going to talk about a very interesting topic. And if you're on hormone replacement therapy as a middle age woman, you're going to want to listen. H.R.T can actually induce weight gain. And going on H.R.T doesn't necessarily promise weight loss. And so I'm going to break it down for you today on this episode. So let's jump in. You are tuned into the Dr. Tina show with Dr. Tina
0:22.4	Moore. For more, visit Dr.tina.com. Okay, we're just going to hop right into it. I'm going to
0:31.1	get personal here. I spent my entire life as a very low hormone girly. I have been testing my hormones since my 30s,
0:40.0	and they have always come back, just bone dry. I am a low hormone girly. I feel best low hormone.
0:45.8	I don't tend to do well on hormones. And going all the way back to college days when I was on oral birth control, contraceptive did
0:57.4	terribly on it, had to discontinue it almost immediately, gained a ton of weight on it like
1:02.4	that.
1:04.1	Fast forward to years later, I'm pregnant, blew up like a balloon during my pregnancy, did
1:10.6	not enjoy it.
1:11.4	Was not one of those women who was like, oh, being pregnant feels so great, did not feel
1:14.5	great.
1:14.9	My autoimmune disease was not happy.
1:16.8	None of my body was happy pregnant.
1:18.7	Did not enjoy it at all.
1:21.4	It was a rough go.
1:24.5	Had my beautiful daughter couldn't lose a pound. Was not one of those women who went straight into breastfeeding and everything was great and lost all the weight.
1:33.1	Didn't happen.
1:34.2	Didn't actually lose a pound until I discontinued breastfeeding and I dropped 10 pounds like that.
1:39.8	Just boom, gone.
1:41.4	And in every situation that I just shared with you am going to continue this story,
1:45.8	the weight gain or loss is like that.
1:48.3	So I know it's the hormones.
	...

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