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The Human Upgrade with Dave Asprey

Web3 & the Future of Genetics: AI, Blockchain & Data Ownership with Nillion : 1271

The Human Upgrade with Dave Asprey

Dave Asprey

Fat, Health & Fitness, Meditation, Biohacking, Lifestyle, Diet, Science, Self-improvement, Fasting, Nutrition, Hacking, Fitness, Brain, Wellness, Education

4.67.3K Ratings

🗓️ 17 April 2025

⏱️ 94 minutes

🧾️ Download transcript

Summary

Your DNA, health data, and digital identity are encrypted, monetized, and weaponized against you. 

But what if there was a way to take it back… and hack the system? 

In this mind-expanding episode, Dave sits down with two elite hacker-founders—Michael Tiffany, CEO of Fulcra.ai, and Vishakh, founder of Monadic DNA—to explore a radical shift in the way we store, protect, and use our most personal data. 

Together, they break down the Web3 tech stack powering this revolution. Enter Nillion, a distributed, privacy-preserving compute network that allows you to share and analyze your encrypted data… without ever giving it away. 

From genomic privacy to AI sovereignty, this episode exposes the hidden architecture of control—and how to escape it. You’ll learn how cutting-edge blockchain and cryptography are rewriting the rules of ownership, consent, and even identity itself. 


What You’ll Learn in This Episode: 

• Why your DNA is already in government databases—and how long they keep it 

• How Nillion enables secure computation on private data 

• What it means to build a “cybernetic operating system” for your body 

• Why Fulcra.ai is building the orchestration layer of human optimization 

• How Monadic DNA helps you profit from your genetics—without giving them away 

• Why owning your data is the next frontier of biohacking 

• The surprising connection between decentralization, health freedom, and consciousness 

• How to join the movement toward true data sovereignty 


If you’ve ever felt like you’re giving away too much to big tech, big pharma, or just the internet itself—this conversation will change how you see your data… and your body. 


**Join the Fulca sleep study today! Visit https://fulcra.ai/sleep to sign up** 

**Get a 30% discount on Fulca with code “DAVE”!  


SPONSORS 

-IGNITON | Go to https://www.biohackingconference.com/ and get your tickets while there are still great discounts available. Learn more at https://igniton.com/.  

-Calroy | Head to https://calroy.com/dave for an exclusive discount. 


Resources:  

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ 

Fulcra Dynamics Website –  https://www.fulcradynamics.com/ 

MonadicDNA Website: https://monadicdna.com/ 

2025 Biohacking Conference: https://biohackingconference.com/2025 

Danger Coffee: https://dangercoffee.com 

Dave Asprey’s Website: https://daveasprey.com 

Dave Asprey’s Linktree: https://linktr.ee/daveasprey 

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com 

Own an Upgrade Labs: https://ownanupgradelabs.com 

Upgrade Labs: https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com 

 

Timestamps: 

• 00:00 – Trailer 

• 02:01 – Intro 

• 02:26 – Data Privacy & AI: The Big Shift 

• 03:21 – Meet Michael Tiffany 

• 04:41 – Cybernetic Operating Systems 

• 05:13 – Wearables & Personal Augmentation 

• 08:21 – Meet Vishakh: DNA Privacy Mission 

• 09:25 – Why Genetic Data Needs Protection 

• 11:30 – New Tech: Encryption & Privacy Tools 

• 16:13 – How Multi-Party Compute Works 

• 41:58 – Emergence: Behavior & Systems 

• 49:11 – Meditation & Mental Reprogramming 

• 50:20 – Distributed Computing & Biology 

• 56:15 – Environment Shapes Potential 

• 57:57 – Empowering Individuals at Scale 

• 01:00:31 – Biohacking Meets Inner Awareness 

• 01:04:01 – The Dark Side of DIY Mind Hacks 

• 01:06:09 – Future of Biohacking & Community

• 01:12:28 – Integrating Genetic & Life Data 

• 01:20:39 – Why We Started Biohacking 

• 01:25:01 – Favorite Current Biohacks 

• 01:31:41 – Final Thoughts & Resources 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Transcript

Click on a timestamp to play from that location

0:00.0

There are so many companies now that can reconstruct facts about you purely based off your DNA.

0:04.9

In all 50 states across the United States, all newborns are genetically sequenced by law.

0:09.5

And the state in New York retains the newborn's DNA by law.

0:12.7

What if your DNA, your memories, your entire life wasn't truly yours?

0:17.2

What if the most intimate parts of you, your health, your history, your potential, were locked inside systems you don't control and watched by people you've never met who sell your very essence without you even knowing?

0:30.2

Today, you'll hear from two pioneers building a different future.

0:34.2

Michael Tiffany brilliantly helped take down the biggest botnets in internet history.

0:39.3

He's a legendary hacker who built tools to protect millions of people from digital attacks.

0:44.8

Many of us feel at the mercy of the algorithm.

0:49.4

Now he's building Volkra, a private vault for all of the data your life creates, encrypted,

0:56.0

yours, and always under your control. Vishak is the founder of monadic DNA. It's a new way to

1:01.6

explore your genetic code so you can have better health and longer life without ever giving up

1:07.2

your privacy or letting someone else copy your DNA. They're not just building apps.

1:12.3

They're building a new kind of internet. One where your data works for you, where it's owned by you

1:17.8

and no one can take it against your will. Powered by Nillian, a radical breakthrough in crypto that

1:23.9

lets computers analyze private data without ever exposing it.

1:28.3

Even if you don't use Nellion, you'll end up re-inventing Nileon.

1:30.3

They're not just protecting your data.

1:32.3

They're rebuilding the internet around you.

1:35.3

Because your identity, your biology, your future should never belong to someone else.

1:40.3

This is the future of privacy, of health, of you owning yourself, your data,

1:46.9

your DNA, your rules. It's time to take it all back. In modern life, each of us as ordinary

...

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