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This Week in Startups

We Asked 3 Experts How to Get More Value out of OpenClaw | E2253

This Week in Startups

Jason Calacanis

Technology

4.21.4K Ratings

🗓️ 21 February 2026

⏱️ 69 minutes

🧾️ Download transcript

Summary

This Week In Startups is made possible by:

Gusto - https://Gusto.com/twist

Circle - https://circle.so/twist

Northwest Registered Agent - https://northwestregisteredagent.com/twist

Today’s show:

*Getting OpenClaw set up and running without destroying your bank account is one thing.

But now that you have your agent or swarm operational, how can you use them to get real work done?

We have three builders who are going to show you how to maximize your OpenClaw output!

GUESTS:

Jordy Coltman: Viral X author and creator of the WeeklyClaw newsletter

Jesse Leimgruber: Creator of the OpenHome.com smart speaker and kit

Tremaine Grant: Founder/CEO of Pulse

PLUS, on Off Duty, Lon and Jason talk “Knight of the 7 Kingdoms” and “The Pitt,” react to the “Mandalorian and Grogu” trailer, and check out some of Jason’s favorite headphones and earbuds.

Timestamps:

00:40 We’re gonna show you how to maximize your IRL OpenClaw productivity

00:50 Even AI skeptic Lon is blown away by OpenClaw’s power

01:46 Jordy Coltman’s top time-wasting mistakes made by OpenClaw beginners

03:00 Why Jordy thinks new hardware is the best home for your agents

05:38 Why Jason thinks “OpenClaw is a box” is coming soon

08:29 Tremaine Grant of Pulse demos his “virtual office” interface and the “Heartbeat Protocol”

00:10:15 Gusto - Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.

00:15:16 What’s really happening when agents “chat” together?

00:18:53 Jesse Leimgruber’s demos his OpenHome AI smart speakers

00:19:47 Circle.so - The easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off the Circle Plus Plan by going to http://circle.so/twist.

00:22:55 Freeing agents from screens and making them proactive

00:29:43 Northwest Registered Agent - Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at www.northwestregisteredagent.com/twist

00:30:58 Why Jason wants his agent to read Slack and emails to him

00:50:05 Who polices autonomous agents? Other agents?

00:53:32 Jason and Lon’s thoughts on “Knight of the Seven Kingdoms”

00:56:20 Lon’s favorite picks from Quentin Tarantino’s Top 10 movies

01:01:13 “The Mandalorian and Grogu” trailer reaction

01:05:22 Jason’s favorite earbuds and headphones

Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.com

Check out the TWIST500: https://www.twist500.com

Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp

Follow Lon:

X: https://x.com/lons

Follow Alex:

X: https://x.com/alex

LinkedIn: ⁠https://www.linkedin.com/in/alexwilhelm

Follow Jason:

X: https://twitter.com/Jason

LinkedIn: https://www.linkedin.com/in/jasoncalacanis

Thank you to our partners:

00:10:15 Gusto - Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.

00:19:47 Circle.so - The easiest way to build a home for your community, events, and courses — all under your own brand. TWiST listeners get $1,000 off the Circle Plus Plan by going to http://circle.so/twist.

00:29:43 Northwest Registered Agent. Get more when you start your business with Northwest. In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity — Learn more at www.northwestregisteredagent.com/twist

Check out all our partner offers: https://partners.launch.co/

Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland

Check out Jason’s suite of newsletters: https://substack.com/@calacanis


Transcript

Click on a timestamp to play from that location

0:00.0

All right, everybody, welcome back to Twist. It is Friday, February 20th. Today, we are going to continue

0:06.2

talking about OpenClaw. My co-host, Lon Harris, is with us again, and we've been talking a lot

0:12.2

about setting up OpenClaw safely. We are now in week three of this incredible transition,

0:18.8

this incredible paradigm shift, to having agents going out and doing

0:23.3

real world things for you. We call them replicants here on the show. And today we have three

0:28.1

builders who are going to show us how to maximize your open claw output because open claw

0:34.2

burns a lot of tokens very quickly and it gets very expensive as we talked about on

0:39.0

the all-in podcast as a viral clip of me and Chimov talking about hey these tokens lawn could

0:44.9

outpace the actual salary of a developer very quickly the way this is going so this is an acute issue

0:52.7

this week in startups is brought to you by Northwest Registered Agent.

0:57.2

Get more when you start your business with Northwest.

1:00.1

In 10 clicks and 10 minutes, you can form your company and walk away with a real business identity.

1:05.4

Learn more at Northwest Registeredagent.com slash twist.

1:10.1

Circle.

1:10.7

Circle gives you everything you need to build and scale your community-led business.

1:14.9

Twist listeners get $1,000 off the Circle Plus plan at circle.s.

1:21.5

Gostow.

1:22.1

Check out the online payroll and benefits experts with software built specifically for small business and startups.

1:28.8

Try Gusto today and get three months free at gusto.com slash twist.

1:33.4

Okay, so cue up our first guest.

1:35.1

Yeah, so I think we have a perfect guest to talk about this, especially in terms of how to

1:40.4

maximize your open cloth and how to avoid the big time wasting mistakes that so many

...

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