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Finding Genius Podcast

VistaGen – On a Mission to Produce Safer & Faster Acting Next-Gen Medicines

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 4 April 2017

⏱️ 32 minutes

🧾️ Download transcript

Summary

VistaGen Therapeutics is a clinical-stage biopharmaceutical company concentrating on developing new generation medicines for depression and other central nervous system (CNS) disorders. The lead CNS product candidate, AV-101, is a new generation antidepressant drug candidate in Phase 2 development. AV-101's mechanism of action is fundamentally differentiated from all FDA-approved antidepressants and atypical antipsychotics used adjunctively to treat major depressive disorder (MDD), with potential to drive a paradigm shift towards a new generation of safer and faster-acting antidepressants.
In addition to the AV-101 programs, VistaStem, VistaGen's wholly owned subsidiary, is focused on applying human pluripotent stem cell technology, internally and with collaborators, to discover, rescue, develop and commercialize proprietary new chemical entities (NCEs), including small molecule NCEs with regenerative potential, for CNS and other diseases, and cellular therapies involving stem cell-derived blood, cartilage, heart and liver cells. VistaGen is utilizing its CardioSafe 3D to participate in the FDA's Comprehensive in-vitro Proarrhythmia Assay (CiPA) initiative designed to change the landscape of nonclinical drug development by providing a more complete and accurate assessment of potential drug effects on cardiac risk using stem cell-derived heart cells and in vitro ion channel data.
In this podcast, Dr. Snodgrass discusses VistaStem's stem cell technology applications as well and their CardioSafe 3D™ program.
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Transcript

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0:00.0

Welcome to Almost Here, Round the Corner of Future Technology Podcasts with Richard Jacobs.

0:07.0

Future Technologies always to transform our lives for better or worse are the focus of this podcast.

0:13.0

Almost here means these technologies are now here and starting to be used.

0:18.0

We're just around the corner.

0:19.0

From Bitcoin to artificial intelligence, 3D around the corner, from Bitcoin to artificial intelligence,

0:22.0

3D printing, blockchain, virtual reality, and more.

0:26.1

Hello, this is Richard Jacobs with Future Tech Podcast.

0:29.5

My guest today is Dr. Ralph Snodgrass, founder and president of Vistigen Therapeutics.

0:35.9

Dr. Snigras, how you doing?

0:39.3

Doing very well, Richard. Thanks very much.

0:40.3

I appreciate talking to you today.

0:42.3

Yeah.

0:43.3

So if you would let listeners know what are the main project

0:48.3

or projects at Vistigen, what are you guys working on?

0:51.3

Sure.

0:52.3

Well, Vistigen is a NASDAQ-LESTED BIO-Farmaceutical company that's developing small molecule

1:01.5

drugs for major CNS conditions.

1:05.6

We're in phase two clinical studies for a lead drug candidate in major depression and has also applications

1:14.4

in other CNS indications such as neuropathic pain, epilepsy, and neurodegenerative diseases

1:23.8

like Parkinson's and Huntington's disease.

1:29.0

I think what I want to talk to you about today is about some of our stem cell technologies.

1:36.5

Vista stem is a wholly owned subsidiary of Vistigen.

...

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