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Science Quickly

Viruses Hijack the Body's Response to Mosquito Bites

Science Quickly

Scientific American

Science

4.41.4K Ratings

🗓️ 22 June 2016

⏱️ 2 minutes

🧾️ Download transcript

Summary

When immune cells rush to the site of a mosquito bite, viruses hijack the cells and turn them into viral factories—in mice, at least. Christopher Intagliata reports. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

This is scientific American's 60 second science.

0:05.0

I'm Christopher in Tagyatta.

0:07.0

Chances are you've had the opportunity to study firsthand

0:10.0

the swollen ichy welt left by a mosquito bite and now scientists have two.

0:15.6

Well we haven't studied itching yet in our in our laboratory studies.

0:19.8

Clive McKimme an immunologist at the University of Leeds in England.

0:23.5

What we've shown is that the inflammation associated with bites is not good for you as a host

0:31.4

and it gives a virus an advantage.

0:33.0

To understand why, let's back up to mosquito spit.

0:36.0

Now I know it's a little disgusting to think about, but when a mosquito bites you,

0:40.0

they're actually spitting out quite a lot of saliva into your skin.

0:44.8

That saliva can contain viruses like Zika or chicken guinea and viruses and the

0:49.8

tissue damage from the bite are a rallying cry for the immune system.

0:54.0

McKimme and his colleagues studied that immune response in mice,

0:57.0

and they found that when immune cells show up at the bite,

1:00.0

the viruses infect them and turn those immune cells into factories for further virus replication.

1:06.4

Your own immune system which is meant to help your body defend itself against infection

1:11.4

seems to be inadvertently promoting an aspect of a virus infection.

1:17.0

Overall the inflammation resulted in 10 times more virus in the mice compared to being inoculated

1:21.9

with the virus without a bite. The study is in the virus without a bite. The study is in the journal Immunity. More viruses

1:27.9

means a higher chance they'll infect your organs and other mosquitoes too. So McKimmy says it might be worth testing a cheap anti-inflammatory,

1:36.0

like a topical ibuprofen cream to see if it cuts virus numbers.

...

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