Hello and welcome to the zero to finals podcast. My name is Tom and in this episode I'm going to be talking to you about vasculitis. And you can find written notes on this topic at zero to finals.com slash vasculitis or in the rheumatology section of the second edition of the zero to finals medicine book.

So let's get straight into it.

Vascularisclitis describes inflammation of the blood vessels.

Various specific diseases cause vasculitis, and these can be categorized based on whether they affect

the small, medium or large vessels.

Let's start with a summary of the different types of vasculitis.

Hennock-Shonline purpura affects the small vessels, and the key features are purpura, which is a non-blanching rash,

and IGA nephritis. Microscopic polyangitis affects the small vessels. It's associated with

P-ancher antibodies and the key features are glomerula nephritis in the kidneys and diffuse alveola hemorrhage

in the lungs. Granulomatosis with polyangitis affects the small vessels. It's associated with

sea anchor antibodies, and the key features are nasal symptoms,

respiratory symptoms, and glomerulinephritis in the kidneys.

Eocinophilic granulomatosis with polyangitis affects the small vessels.

It's associated with P-anchor antibodies and raised eosinophils,

and the key features are late-onset asthma and sinusitis and rhinitis in the nose.

Polyarthritis nodosa affects the medium-sized vessels vessels and the key features are renal impairment,

hypertension or high blood pressure, cardiovascular events and tender skin nodules.

Kawasaki disease affects the medium-sized vessels and the key features are a high fever for more

than five days, a widespread rash, bilateral conjunctivitis, a strawberry tongue and coronary

artery aneurysms. Giant cell arteritis affects the large vessels. The lab finding is a raised ESR or erythricide sedimentation rate

and the key features are unilateral headache, scalp tenderness and vision loss.

And finally, Takayasu's arthritis affects the large vessels and the key features are that the

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