Hello and welcome to the zero to finals podcast. My name is Tom and in this episode I'm going to be

talking to you about Shogren syndrome. And you can find written notes on this topic at

zero to finals.com slash showgrins or in the rheumatology section of the second edition of the Zero to Finals

Medicine book. So let's get straight into it.

Shogren syndrome is an autoimmune condition that affects the exocrine glands, notably the

lacrimal glands and the salivary glands, and it causes symptoms of a dry mouth and dry eyes.

It can also cause vaginal dryness.

Dry eyes and a dry mouth can be called sicker symptoms.

It can also cause dry skin, joint pain and stiffness.

Shogran syndrome is more common in women and typically presents in middle age.

Primary Shogran's is where the condition occurs on its own.

Secondary Shogran's is where it occurs due to other conditions,

such as systemic lupus erythematosis and rheumatoid arthritis.

Antibodies associated with chograns are anti-S-S-A antibodies, also called anti-Roe antibodies, and anti-S-B antibodies, also called anti-L-A antibodies.

Let's talk about the Shermer test.

The Shermer test involves inserting folded filter paper under the lower eyelid with the end hanging out.

Moisture from the eye will travel by diffusion along the filter paper.

After five minutes, the distance that the moisture from the eye travels along the filter paper is measured.

In a healthy young adult, 15mm is expected.

Less than 10mm is significant and suggests Shogran syndrome.

Next let's talk about management.

The diagnosis is typically made based on the clinical features and the

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