Welcome to the Mad in America podcast, your source for science, psychiatry, and social justice.

Hello, I'm Zanobia Moral and news reporter at Madin America, and I'm pleased to have with me, Dr.

Rance Trudeau, professor at the University of Ottawa in Canada,

who is here to tell us more about a recent study he conducted alongside a team of researchers

led by Dr. Marilyn Bericheng that has implications on the long-term impact of antidepressant

drug exposure. The study will be discussing is titled Transgenerational Hypochortisolism and behavioral

disruption are induced by the antidepressant fluoxidine in male zebrafish. Dr. Trudeau is the research

chair in neuroendocrinology at the university, where he studies the ways in which the brain

regulates hormonal activity and fish

and frauds.

Such analyses offer important implications and insights into environmental and human health,

because these hormonal systems are shared across species.

Welcome, Dr. Trudeau.

Thanks for joining us.

It's nice to be here.

We really appreciate having you here to tell us more about this interesting study.

Could you start by giving us a brief overview of the study, what you did, and what you found?

Yes, we've been interested in how pollutants get into the environment,

especially pollutants that we generate through our use of pharmaceuticals.

So when you take any pill, aspirin or Prozac or what have you, it goes into the sewage treatment plant.

It degrades a little bit, but not all. And then it's released to the environment, to lakes or streams or rivers. So we started looking at fluoxetine, the active ingredient of the drug Prozac, quite a few years ago. So our

angle was much more on the impacts on the environment. But then, of course, you realize that

...