Vaccine Wars | The Hype Cycle | 2

Business Wars

Wondery

History, Business, David Brown, Management

4.6 • 13.2K Ratings

🗓️ 21 April 2021

⏱️ 32 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

It’s 25 years before the pandemic and at the University of Pennsylvania a Hungarian biochemist is fighting a one-woman campaign to figure out how to create mRNA vaccines.

But no one wants to fund her research and every lab rat she injects with mRNA dies.

Now, she must decide between her career and her belief in mRNA’s medical potential. And her choice will change the world.

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Transcript

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0:00.0	Hey, prime members, you can listen to business wars, add free on Amazon music.
0:04.8	Download the app today.
0:07.0	Philadelphia, 1995.
0:17.7	25 years before the pandemic.
0:22.2	Catalan Carrico heads down the corridors of the University of Pennsylvania toward her boss's
0:27.2	office.
0:28.2	Carrico is a 40-year-old Hungarian biochemist.
0:31.8	She came to America 10 years ago to further her research into messenger RNA, mRNA for
0:37.5	short.
0:39.0	mRNA is a cell's internal message delivery service, and Carrico believes these strands of genetic
0:45.1	material could transform medicine.
0:48.7	The job of mRNA is to ferry the information written in our DNA to ribosomes, the tiny
0:54.1	protein factories that exist inside our cells.
0:57.8	The mRNA tells the ribosomes which proteins to produce.
1:01.8	Without mRNA, the proteins that do everything from growing hair to regulating digestion don't
1:08.0	get made.
1:09.7	Carrico first learned about mRNA in the 1970s as an undergraduate student.
1:14.9	At the time, scientists were full of hope that mRNA could be used to create cures and
1:19.7	vaccines.
1:20.7	But these days, Carrico is one of the last true believers.
1:27.2	She knocks on her boss's door and enters.
1:30.0	Catalan, thanks for coming.
	...

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