Using Fasting Strategies to Reduce Inflammaging and Longevity with Dr. Joseph Antoun
Dr. Jockers Functional Nutrition
Dr. Jockers
4.8 • 688 Ratings
🗓️ 19 August 2025
⏱️ 44 minutes
🧾️ Download transcript
Summary
In this episode, Dr. Jockers sits down with Dr. Joseph Antoun to unpack how fasting strategies, including fasting-mimicking diets, can rejuvenate immune cells, slow down inflammaging, and support overall healthy aging.
You’ll discover how chronic inflammation accelerates aging, why old “zombie” cells cause damage, and how fasting helps clear them out while replacing them with stronger, more resilient ones. The conversation also dives into immunosenescence, what happens when immune cells age, and how this process links to conditions like cancer, cardiovascular disease, and autoimmune disorders.
Dr. Antoun also explains the delicate balance between growth and repair in the body—and why our modern eating patterns keep us stuck in constant growth mode. By leveraging targeted fasting protocols, we can push our bodies toward autophagy, boost cell repair, and open the door to a healthier, longer life.
In This Episode:
00:00 Introduction to Fasting and Cellular Rejuvenation
00:48 Guest Introduction: Dr. Joseph Antoun
04:25 Understanding Chronic Inflammation and Inflammaging
10:10 The Role of Nutrition in Aging and Immune Health
13:13 Fasting Mimicking Diet: Science and Benefits
23:32 Fasting and Autoimmune Diseases
24:35 The Role of Stomach Acid in Digestion
26:28 ProLon and Biological Age Reduction
30:15 ProLon for Diabetes and Chronic Conditions
32:06 How to Use ProLon Effectively
38:06 Current Research and Future Directions
40:49 The Importance of Fasting in Human Health
42:39 Conclusion and Final Thoughts
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"As we age, our immune cells become more sluggish, but fasting helps rejuvenate them, giving you a youthful immune response."
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- Website: https://www.glownaturalwellness.com/
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Transcript
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| 0:00.0 | It's like a company with no money, right? |
| 0:02.4 | First, you have some reserve, some money in the bank. |
| 0:04.7 | The body also has some fat, some glycogen, so it can survive a day or two of fasting. |
| 0:10.0 | A company can survive a couple of weeks with no money leaning on the bank account and the checking and the saving accounts. |
| 0:16.2 | But then when you deplete the reserve, you got to restructure the company. |
| 0:19.8 | You've got to fix it to survive. |
| 0:22.0 | And the body after day two and starting day three of fasting is telling the cells, |
| 0:26.4 | I cannot nourish you any longer. |
| 0:28.7 | You've got to rejuvenate. |
| 0:29.7 | We are in high stress. |
| 0:31.3 | Well, welcome back to the podcast, excited about today's episode. |
| 0:35.2 | We're going to go into some deep stuff, including how to fast for inflammation |
| 0:39.5 | and immune rejuvenation. We're going to talk about what is chronic inflammation and |
| 0:44.7 | inflamaging, how inflammation actually ages us. My guest is Dr. Joseph Antoine from prolonlife.com. |
| 0:52.9 | And we're going to talk all about the immune cells, how they age, |
| 0:56.1 | something called immunosiniscence. We're going to talk about how fasting strategies can be used to |
| 1:01.0 | combat inflammation, how fasting can help damaged organs in autoimmune conditions. We're going to |
| 1:07.1 | talk about what fasting protocols have been shown to improve inflammation. |
| 1:13.7 | And so if you don't know Dr. Joseph Antoine, I've had him on the podcast before. |
| 1:16.6 | His passion is to enhance human longevity. |
| 1:22.4 | And he's the CEO and chairman of the board of L Nutra Inc, a unique nutrition technology company, |
| 1:25.2 | leading the longevity and food as medicine markets. You can find it at prolonlife.com. And Dr. Antoine has |
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