Understanding the Behaviour of Mitochondria - Martin Picard : 565

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Dave Asprey

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🗓️ 7 February 2019

⏱️ 62 minutes

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Summary

Martin Picard, Ph.D. is an Assistant Professor of Behavioral Medicine in Psychiatry and Neurology at Columbia University. For over a decade, Martin has been studying mitochondria and has worked closely with leading experts in the field of mitochondrial research.

In 2015, he joined the faculty at Columbia University where he established the Mitochondrial Signaling Laboratory. He’s currently investigating mechanisms of mind-body interactions, specifically regarding novel principles that underlie mitochondrial responses to stressors, the maintenance of human health, and the influence of mitochondrial defects on complex cellular and physiological processes including aging.

In this episode, we talk about the exciting research happening in his lab and what mitochondria tell us about our health.

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Transcript

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0:00.0	You're listening to Bulletproof Radio with Dave Asprey.
0:16.3	Today's cool fact of the day is that it turns out that it's not just your mom who passes
0:21.4	along mitochondrial DNA.
0:23.9	If you read my book Headstrong about mitochondria and how to turn on your brain, you learned what
0:29.1	we all commonly believe that mitochondria comes from mom.
0:32.4	In some cases, you might have your dad's mitochondria.
0:36.0	They're just not that common.
0:38.0	So leave it to dads to break the rules and textbooks.
0:40.8	Turns out, fathers and three unrelated families have been documented to pass their mitochondria.
0:46.1	Those tiny little things we like to call energy factories found in cells onto their children.
0:51.4	If you're familiar with lots of the stuff I talk about, mitochondria do a lot more than
0:55.0	make energy.
0:56.0	It's actually the frontline environmental sensors.
0:58.3	As you're going to hear about in today's interview, they do more than that when it comes
1:02.4	to interacting with your brain.
1:04.9	Scientists have long thought that kids just always got mitochondria exclusively from
1:10.1	others because mitochondria and sperm get destroyed during the fertilization of the egg.
1:17.0	This happened because the mitochondrial disease researcher said, wait, how is this possible
1:20.8	that we could have paternal DNA in a woman?
1:24.5	They did a bunch of work on this stuff.
1:26.8	They figured out that that woman's cells had some mitochondrial from mom and some from
1:31.1	her dad.
	...

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