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Finding Genius Podcast

Understanding the Ancient Disease of Malaria—Purnima Bhanot—Associate Professor, Rutgers New Jersey Medical School

Finding Genius Podcast

Richard Jacobs

Medicine, Health & Fitness

4.41K Ratings

🗓️ 3 August 2020

⏱️ 46 minutes

🧾️ Download transcript

Summary

Associate Professor at Rutgers New Jersey Medical School, Purnima Bhanot, joins the show to discuss all things malaria. In this episode, you will discover:

  • What the malaria parasite does once it enters the human body
  • How many deaths continue to occur annually as a result of malaria, and why approximately 80% of these deaths are of children under age five
  • When and how a human can build an immune response and avoid the worst consequences of malaria
  • How the insecticide DDT was used for malaria control, and how it actually led to a resurgence of malaria in countries that had nearly eradicated it

Malaria has plagued the human species for as long as we have known agriculture. With about 200 million cases and 400,000 deaths per year, it has a staggering toll on human life, but only half of the toll it had about a decade ago.

Malaria is caused by a parasite called Plasmodium, which is transmitted to humans through the bite of the Anopheles mosquito. The disease affects primarily children under the age of five in sub-Saharan Africa, and leads to a number of malaria symptoms, including high fever, chills, anemia, coma, and death.

Bhanot explains the malaria life cycle and exactly how it interacts with the body during subclinical and clinical phases of the disease. She also discusses which populations of individuals are most vulnerable to the disease and why, what sort of control methods have been implemented, how the immune response to the parasite works, whether malaria infects non-human animals, the increasing resistance to antimalarial drugs and how this is being studied, possible malaria treatments, and so much more.

Available on Apple Podcasts: apple.co/2Os0myK

Transcript

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0:00.0

Forget frequently asked questions common sense common knowledge or Google how about advice from a real genius

0:06.8

95% of people in any profession are good enough to be qualified and licensed 5% go and beyond. They become very good at what they do.

0:15.0

But only 0.1% are real Jesus.

0:18.3

Richard Jacobs has made it his life's mission to find them for you.

0:22.3

He hunts down and interviews geniuses in every

0:24.7

field, sleep science, cancer, stem cells, ketogenic diets and more. Here come the geniuses.

0:30.1

This is the Finding Genius Podcast.

0:33.0

That is Richard Jacobs.

0:35.0

Hello, this is Richard Jacobs with the Finding Genius Podcast.

0:41.0

My guess today is Miss Prima Bonoque. She's an

0:44.3

associate professor at Rutgers and where you talk about the malaria, the

0:48.8

biology of the malaria parasite. So Prunema, thanks for coming. Thank you for having me.

0:54.6

Yeah, for listeners that may not know much about malaria, think about it, what is it and

0:59.2

you know, how many people does it affect? So malaria is actually a really old disease. It's been around

1:06.0

with humans for as long as we have known agriculture.

1:13.0

In a good year, which means more recently,

1:17.0

it has, there have been more than 200 million cases of malaria

1:22.0

each year, and each year that results in the

1:26.7

death of over 400,000 people. As recently as 10 years ago, these numbers were almost double of what they are currently.

1:38.0

But even with that progress, you can tell this is a disease that takes a huge toll on human life, mostly in sub-Saharan

1:48.1

Africa and mostly of children below the age of five.

1:53.0

Right.

...

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